Lexaria Bioscience (NASDAQ: LEXX), a global innovator in drug-delivery platforms, has begun a new study, EPIL-A21-1,designed to evaluate whether its DehydraTECH(TM)-CBD (“CBD”) indicates superior ability to reduce seizure activity compared to both generic cannabidiol and Epidiolex. Epidiolex is the only CBD medication approved by the U.S. Food and Drug Administration (“FDA”) for the treatment of seizures associated with Lennox-Gastaut syndrome and Dravet syndrome, two rare and severe forms of pediatric epilepsy. Among those involved in the study are respirology and neurobiology experts. According to the announcement, the team of investigators will carefully analyze how DehydraTECH-CBD compares with Epidiolex in treating seizures. LEXX noted that the company developed its seizure program because of the significant gains in systemic delivery and brain uptake that had been seen repeatedly in its own studies as well as other studies comparing DehydraTECH-CBD with concentration-matched controls. Lexaria also announced that it has received its first patent award for DehydraTECH in Mexico as well as another patent in Japan; the Mexico award protects the proprietary drug-delivery system for use with cannabinoids and nicotine while the Japan patent covers the use of DehydraTECH utilizing nonpsychoactive cannabinoids, nicotine, vitamins or nonsteroidal anti-inflammatory (“NSAID”) substances. The Japan award is the fifth patent the company has been awarded in 2021. The company currently has 23 granted patents from the United States, Australia, the European Union, India, Japan and Mexico that protect DehydraTECH.

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About Lexaria Bioscience Corp.

Lexaria Bioscience’s patented drug-delivery technology, DehydraTECH(TM), improves the way active pharmaceutical ingredients (“APIs”) enter the bloodstream by promoting more effective oral delivery. Since 2016, DehydraTECH has repeatedly demonstrated the ability to increase bioabsorption of cannabinoids and nicotine by 5 to 10 times as well as reduce time of onset from one to two hours to minutes and mask unwanted tastes. The delivery systems are also being evaluated for orally administered, anti-viral drugs and nonsteroidal, anti-inflammatory drugs (NSAIDs) and more. DehydraTECH has also evidenced an ability to deliver some drugs more effectively across the blood brain barrier. Lexaria operates a licensed in-house research laboratory and holds a robust intellectual property portfolio with 21 patents granted and more than 50 patents pending worldwide. For more information about the company, please visit www.LexariaBioscience.com.

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