SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT

                       PURSUANT TO SECTION 13 OR 15(D) OF
                       THE SECURITIES EXCHANGE ACT OF 1934

         Date of Report (Date of earliest event reported): April 6, 2009

                        MERIDIAN INTERSTATE BANCORP, INC.
                        ---------------------------------
               (Exact Name of Registrant as Specified in Charter)

         Massachusetts                001-33898                 20-4652200
  -----------------------------   ----------------------     ---------------
(State or Other Jurisdiction)     (Commission File No.)       (I.R.S. Employer
      of Incorporation)                                      Identification No.)


10 Meridian Street, East Boston, Massachusetts                      02128
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(Address of Principal Executive Offices)                          (Zip Code)

Registrant's telephone number, including area code:  (617) 567-1500
                                                     --------------



                                 Not Applicable
                                 --------------
          (Former name or former address, if changed since last report)

Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

[  ] Written communications  pursuant to Rule 425 under the Securities Act (17
     CFR 230.425)

[  ] Soliciting  material  pursuant to Rule 14a-12 under the Exchange Act (17
     CFR 240.14a-12)

[  ] Pre-commencement  communications  pursuant  to Rule  14d-2(b)  under the
     Exchange Act (17 CFR 240.14d-2(b))

[  ] Pre-commencement  communications  pursuant  to Rule  13e-4(c)  under the
     Exchange Act (17 CFR 240.13e-4(c))






Item 1.02 Termination of a Material Definitive Agreement
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Meridian Interstate Bancorp, Inc. (the "Company") reports that Leonard V. Siuda,
Treasurer  and Chief  Financial  Officer of the Company and East Boston  Savings
Bank (the "Bank"), a subsidiary of the Company, will resign and retire effective
April 29, 2009.

Mr. Siuda was employed by the Bank  pursuant to an employment  agreement,  dated
December 29, 2003.  In connection  with the  resignation  and  retirement of Mr.
Siuda, his employment  agreement also will be terminated,  effective as of April
29,  2009,  except the terms of  Section 7 of his  employment  agreement,  which
contain  noncompetition,  confidential  information and cooperation  provisions,
will  continue to apply.  In  accordance  with his  employment  agreement and in
exchange for a release of any claims against the Company and the Bank, Mr. Siuda
will be entitled to receive the  severance  benefits  described  in Item 5.02 of
this Current Report.

The Company also  reports  that in  connection  with the  termination  of Philip
Freehan's employment, as previously disclosed on the Company's Current Report on
Form 8-K filed with the Securities and Exchange Commission on February 26, 2009,
his employment  agreement  terminated effective March 31, 2009, except the terms
of  Section  7  of  his  employment  agreement,  which  contain  noncompetition,
confidential information and cooperation provisions,  will continue to apply. In
exchange for a release of any claims  against the Company and Bank,  Mr. Freehan
and the Bank have  negotiated  a release  and  separation  agreement  which will
entitle Mr. Freehan to receive the severance  benefits described in Item 5.02 of
this Current Report.

Item 5.02 Departure of Directors or Principal  Officers;  Election of Directors;
Appointment of Certain Officers; Compensatory Arrangements of Certain Officers
--------------------------------------------------------------------------------

On April 7, 2009, Meridian Interstate  Bancorp,  Inc. (the "Company")  announced
that Leonard V. Siuda,  Treasurer and Chief Financial Officer of the Company and
East Boston Savings Bank (the "Bank"), a subsidiary of the Company,  retired and
resigned from the Company and the Bank effective as of April 29, 2009.

In exchange for a release of any claims against the Company and the Bank and Mr.
Siuda agreeing to the  restrictions  set forth under Section 7 of his employment
agreement,   which  include   noncompetition,   confidential   information   and
cooperation  provisions,  the Bank entered into a Separation  Agreement with Mr.
Siuda. The Separation  Agreement  provides that the Bank will continue to pay an
amount  equal to his  current  rate of base  salary  in equal  installments  for
twenty-four  months,  which equals a gross amount of $364,226 less  withholding.
Mr.  Siuda is also  entitled  to the  following  payments,  which he would  have
received  regardless of whether he entered into a Separation  Agreement,  all of
which are referenced in the Separation  Agreement:  (i) compensation  earned but
not yet paid as of his  resignation  date,  (ii) a lump sum  payment  under  his
supplemental executive retirement agreement,  in the amount of $1,281,818,  less
withholding,  (iii)  the  continuation  of  split  dollar  and bank  owned  life
insurance  policies,  which  provide  a death  benefit  equal  to  $455,283  and
$364,226,  respectively,  and (iv) the  continuation of long term care insurance
for Mr. Siuda and his spouse.  It is  anticipated  that an  estimated  after-tax
expense of $657,362  associated  with the  foregoing  will be  recognized by the
Company in the first quarter of 2009.



On April 7, 2009, the Company also announced that Philip Freehan, Executive Vice
President  of the Company and the Bank,  resigned  from all  positions  with the
Company and the Bank effective as of March 31, 2009. As previously  disclosed on
the Company's  Current Report on Form 8-K filed with the Securities and Exchange
Commission on February 26, 2009, Mr.  Freehan  submitted a letter to the Bank on
February 20, 2009  announcing his  resignation and termination of his employment
as an officer of the Bank.

In exchange for a release of any claims against the Company and the Bank and Mr.
Freehan agreeing to the restrictions set forth under Section 7 of his employment
agreement,   which  include   noncompetition,   confidential   information   and
cooperation provisions, the Bank entered into a Separation and Release Agreement
with Mr.  Freehan,  which was  executed  on April 6, 2009.  The  Separation  and
Release  Agreement  provides  that the Bank will pay Mr.  Freehan  $53,234  less
withholding,  which  represents Mr. Freehan's base salary from February 27, 2009
to May 15, 2009, in a lump sum within five business days of Mr. Freehan  signing
the  agreement  and a gross  amount  of  $123,580  over six (6)  months in equal
amounts, with the first payment commencing on June 15, 2009. Mr. Freehan is also
entitled to the following  payments,  which he would have received regardless of
whether he entered into a  Separation  and Release  Agreement,  all of which are
referenced in the Separation and Release Agreement: (i) a lump sum payment under
his supplemental  executive retirement  agreement,  in the amount of $1,324,821,
less  withholding,  (ii) the  continuation  of split  dollar and bank owned life
insurance  policies,  which  provide  a death  benefit  equal  to  $617,900  and
$494,320,  respectively,  and (iii) the continuation of long term care insurance
for Mr. Freehan and his spouse.  It is anticipated  that an estimated  after-tax
expense of $519,076  associated  with the  foregoing  will be  recognized by the
Company in the first quarter of 2009.

The foregoing  description  of the  Separation  Agreement  entered into with Mr.
Siuda and the Separation and Release Agreement entered into with Mr. Freehan are
qualified  in its entirety by reference  to the  agreements  attached  hereto as
Exhibits 10.1 and 10.2 of this Current Report,  and is incorporated by reference
into this Item 5.02. The  information  set forth in Item 1.01 is incorporated by
reference in this Item 5.

Item 9.01. Financial Statements and Exhibits.
           ----------------------------------

     (a)  Not Applicable.

     (b)  Not Applicable.

     (c)  Not Applicable.

     (d)  Exhibits:

          Exhibit Number            Description
          --------------            -----------
          Exhibit 10.1              Separation Agreement between East Boston
                                    Savings Bank and Leonard V. Siuda, dated
                                    April 6, 2009.


          Exhibit 10.2              Separation and Release Agreement between
                                    East Boston Savings Bank and Philip F.
                                    Freehan, dated March 31, 2009, and executed
                                    on April 6, 2009.






                                   SIGNATURES

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
Registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned, hereunto duly authorized.

                                        MERIDIAN INTERSTATE BANCORP, INC.



DATE: April 6, 2009                By: /s/ Leonard V. Siuda
                                       -----------------------------------
                                       Leonard V. Siuda
                                       Treasurer and Chief Financial Officer