Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
HSO LIMITED PARTNERSHIP
  2. Issuer Name and Ticker or Trading Symbol
HARVARD BIOSCIENCE INC [HBIO]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
THE CAYMAN CORPORATE CENTRE, 4TH FLOOR, 27 HOSPITAL ROAD
3. Date of Earliest Transaction (Month/Day/Year)
11/16/2007
(Street)

GEORGETOWN, GRAND CAYMAN, E9 00000
4. If Amendment, Date Original Filed(Month/Day/Year)
11/19/2007
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 11/16/2007   P(1)   6,210 A $ 3.8999 3,467,718 D  
Common Stock 11/16/2007   P(1)   7,612 A $ 3.8988 3,475,330 D  
Common Stock 11/16/2007   P(1)   4,567 A $ 3.9063 3,479,897 D  
Common Stock 11/19/2007   P(1)(2)   5,043 A $ 3.741 3,484,940 D  

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
HSO LIMITED PARTNERSHIP
THE CAYMAN CORPORATE CENTRE, 4TH FLOOR
27 HOSPITAL ROAD
GEORGETOWN, GRAND CAYMAN, E9 00000
    X    

Signatures

 /s/HSO Limited Partnership, by Skystone Advisors LLC, Investment Member of the General Partner, by Kerry Nelson, Managing Member   11/20/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) This amendment is being filed in order amend four line-items by correcting (a) a typographical error included in one line-item as to the number of shares purchased and (b) making corresponding revisions to the total amounts listed in column 5 of each of the four line-items based on such corrected number of shares purchased.
(2) The reporting person's purchase of HBIO common stock reported herein was matchable under Section 16(b) of the Securities Exchange Act of 1934, as amended, to the extent of 100 shares, with the reporting person's sale of 100 shares of HBIO common stock on September 25, 2007 (the "Sale"). The reporting person has agreed to pay to HBIO the full amount of the profit realized in connection with the short-swing transactions, less transaction costs, and less amounts previously paid to HBIO by the reporting person in connection with the Sale and a previously disclosed transaction matchable against the Sale.

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