SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No. 2) DOR BioPharma, Inc. -------------------------------------------------------------------------------- (Name of Issuer) Common Stock, par value $0.001 -------------------------------------------------------------------------------- (Title of Class of Securities) 258094101 -------------------------------------------------------------------------------- (CUSIP Number) December 31, 2005 -------------------------------------------------------------------------------- (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: [_] Rule 13d-1(b) [x] Rule 13d-1(c) [_] Rule 13d-1(d) CUSIP No. 258094101 --------------------- 1. NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Silverback Asset Management, LLC 2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) [_] (b) [_] 3. SEC USE ONLY 4. CITIZENSHIP OR PLACE OF ORGANIZATION Delaware NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH 5. SOLE VOTING POWER 0 6. SHARED VOTING POWER 3,837,700* 7. SOLE DISPOSITIVE POWER 0 8. SHARED DISPOSITIVE POWER 3,837,700* 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 3,837,700* 10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES [_] 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 7.6% 12. TYPE OF REPORTING PERSON CO * Silverback Asset Management, LLC ("SAM") serves as investment manager to Silverback Master, Ltd. ("Silverback Master") and certain other private investment vehicles. In its capacity as investment manager of such private investment vehicles, including Silverback Master, SAM may be deemed to be the beneficial owner of securities held by each such private investment vehicle. SAM disclaims beneficial ownership of the securities reported in this Schedule 13G except to the extent of its pecuniary interest therein, and the filing of this Schedule 13G shall not be construed as an admission that SAM is, for the purposes of Section 13(d) or 13(g) of the Act, the beneficial owner of any securities reported in this Schedule 13G except to the extent of its pecuniary interest therein. CUSIP No. 258094101 --------------------- 1. NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Silverback Master, Ltd. 2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) [_] (b) [_] 3. SEC USE ONLY 4. CITIZENSHIP OR PLACE OF ORGANIZATION Cayman Islands NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH 5. SOLE VOTING POWER 0 6. SHARED VOTING POWER 3,108,000 7. SOLE DISPOSITIVE POWER 0 8. SHARED DISPOSITIVE POWER 3,108,000 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 3,108,000 10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES [_] 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 6.1% 12. TYPE OF REPORTING PERSON CO CUSIP No. 258094101 --------------------- 1. NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Elliot Bossen 2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) [_] (b) [_] 3. SEC USE ONLY 4. CITIZENSHIP OR PLACE OF ORGANIZATION United States of America NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH 5. SOLE VOTING POWER 0 6. SHARED VOTING POWER 3,837,700** 7. SOLE DISPOSITIVE POWER 0 8. SHARED DISPOSITIVE POWER 3,837,700** 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 3,837,700** 10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES [_] 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 7.6% 12. TYPE OF REPORTING PERSON IN ** Elliot Bossen is the sole Managing Member of SAM and is primarily responsible for the investment decisions of SAM. Elliot Bossen disclaims beneficial ownership of the securities reported in this Schedule 13G except to the extent of his pecuniary interest therein, and the filing of this Schedule 13G shall not be construed as an admission that he is, for the purposes of Section 13(d) or 13(g) of the Act, the beneficial owner of any securities reported in this Schedule 13G except to the extent of his pecuniary interest therein. CUSIP No. 258094101 --------------------- Item 1(a). Name of Issuer: DOR BioPharma, Inc. ____________________________________________________________________ Item 1(b). Address of Issuer's Principal Executive Offices: 1691 Michigan Ave., Suite 435 Miami, FL 33139 ____________________________________________________________________ Item 2(a). Name of Person Filing: Silverback Asset Management, LLC Silverback Master, Ltd. Elliot Bossen ____________________________________________________________________ Item 2(b). Address of Principal Business Office, or if None, Residence: Silverback Asset Management, LLC 1414 Raleigh Road Suite 250 Chapel Hill, NC 27517 Silverback Master, Ltd. c/o International Fund Services (Ireland) Limited Bishop's Square, Third Floor Redmond's Hill Dublin 2, Ireland Elliot Bossen c/o Silverback Asset Management, LLC 1414 Raleigh Road Suite 250 Chapel Hill, NC 27517 ____________________________________________________________________ Item 2(c). Citizenship: Silverback Asset Management, LLC - Delaware Silverback Master, Ltd. - Cayman Islands Elliot Bossen - United States of America ____________________________________________________________________ Item 2(d). Title of Class of Securities: Common Stock, par value $0.001 ____________________________________________________________________ Item 2(e). CUSIP Number: 258094101 ____________________________________________________________________ Item 3. If This Statement is Filed Pursuant to Rule 13d-1(b), or 13d-2(b) or (c), Check Whether the Person Filing is a: (a) [_] Broker or dealer registered under Section 15 of the Exchange Act. (b) [_] Bank as defined in Section 3(a)(6) of the Exchange Act. (c) [_] Insurance company as defined in Section 3(a)(19) of the Exchange Act. (d) [_] Investment company registered under Section 8 of the Investment Company Act. (e) [_] An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E); (f) [_] An employee benefit plan or endowment fund in accordance with Rule 13d-1(b)(1)(ii)(F); (g) [_] A parent holding company or control person in accordance with Rule 13d-1(b)(1)(ii)(G); (h) [_] A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act; (i) [_] A church plan that is excluded from the definition of an investment company under Section 3(c)(14) of the Investment Company Act; (j) [_] Group, in accordance with Rule 13d-1(b)(1)(ii)(J). Item 4. Ownership. (a) Amount beneficially owned: Silverback Asset Management, LLC - 3,837,700** Silverback Master, Ltd. - 3,108,000** Elliot Bossen - 3,837,700** ______________________________________________________________________ (b) Percent of class: Silverback Asset Management, LLC - 7.6% Silverback Master, Ltd. - 6.1% Elliot Bossen - 7.6% ______________________________________________________________________ (c) Number of shares as to which such person has: Silverback Asset Management, LLC -------------------------------- (i) Sole power to vote or to direct the vote 0 ___________________, (ii) Shared power to vote or to direct the vote 3,837,700 ___________________, (iii) Sole power to dispose or to direct the 0 disposition of ___________________, (iv) Shared power to dispose or to direct the 3,837,700 disposition of ____________________ Silverback Master, Ltd. ----------------------- (i) Sole power to vote or to direct the vote 0 ___________________, (ii) Shared power to vote or to direct the vote 3,108,000 ___________________, (iii) Sole power to dispose or to direct the 0 disposition of ___________________, (iv) Shared power to dispose or to direct the 3,108,000 disposition of ___________________. Elliot Bossen ------------- (i) Sole power to vote or to direct the vote 0 ___________________, (ii) Shared power to vote or to direct the vote 3,837,700 ___________________, (iii) Sole power to dispose or to direct the 0 disposition of ___________________, (iv) Shared power to dispose or to direct the 3,837,700 disposition of ___________________. Item 5. Ownership of Five Percent or Less of a Class. If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities check the following [ ]. N/A _______________________________________________________________________ Item 6. Ownership of More Than Five Percent on Behalf of Another Person. N/A _______________________________________________________________________ Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person. N/A _______________________________________________________________________ Item 8. Identification and Classification of Members of the Group. N/A _______________________________________________________________________ Item 9. Notice of Dissolution of Group. N/A _______________________________________________________________________ Item 10. Certifications. By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having such purpose or effect. SIGNATURE After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. February 14, 2006 ---------------------------------------- (Date) Silverback Asset Management, LLC By: /s/ Elliot Bossen -------------------------------- Name: Elliot Bossen Title: Managing Member Silverback Master, Ltd. By: /s/ Elliot Bossen -------------------------------- Name: Elliot Bossen Title: Director /s/ Elliot Bossen ------------------------------- Elliot Bossen Exhibit A --------- The undersigned agree that this Amendment No. 2 Schedule 13G dated February 13, 2006 relating to the Common Stock, par value $0.001, of DOR BioPharma, Inc. is being filed on behalf of each of Silverback Asset Management, LLC, Silverback Master, Ltd. and Elliot Bossen. February 14, 2006 ---------------------------------------- (Date) Silverback Asset Management, LLC By: /s/ Elliot Bossen -------------------------------- Name: Elliot Bossen Title: Managing Member Silverback Master, Ltd. By: /s/ Elliot Bossen -------------------------------- Name: Elliot Bossen Title: Director /s/ Elliot Bossen ------------------------------- Elliot Bossen SK 04098 0001 643440