--------------------------
                                                             OMB APPROVAL
                                                      --------------------------
                                                      OMB  Number:     3235-0145
                                                      Expires: December 31, 2005
                                                      Estimated  average  burden
                                                      hours per response......11
                                                      --------------------------



                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                              Washington, DC 20549

                                  SCHEDULE 13G

                    Under the Securities Exchange Act of 1934
                               (Amendment No. __)*


                              The Medicines Company
--------------------------------------------------------------------------------
                                (Name of Issuer)

                    Common Stock, par value $0.001 per Share
--------------------------------------------------------------------------------
                         (Title of Class of Securities)


                                    584688105
--------------------------------------------------------------------------------
                                 (CUSIP Number)


                                 March 15, 2006
--------------------------------------------------------------------------------
             (Date of Event which Requires Filing of this Statement)


Check the  appropriate box to designate the rule pursuant to which this Schedule
is filed:

|_|      Rule 13d-1(b)
|X|      Rule 13d-1(c)
|_|      Rule 13d-1(d)

* The remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for any  subsequent  amendment  containing  information  which  would  alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).

                         (Continued on following pages)
                               Page 1 of 27 Pages
                         Exhibit Index Found on Page 28








                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Farallon Capital Partners, L.P.
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page,  however,  is a beneficial  owner only of
                           the securities reported by it on this cover page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            California
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   486,300
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    486,300
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            486,300
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            1.0%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            PN
------------====================================================================



                               Page 2 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Farallon Capital Institutional Partners, L.P.
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page,  however,  is a beneficial  owner only of
                           the securities reported by it on this cover page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            California
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   434,100
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    434,100
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            434,100
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            0.9%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            PN
------------====================================================================



                               Page 3 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================
------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Farallon Capital Institutional Partners II, L.P.
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page,  however,  is a beneficial  owner only of
                           the securities reported by it on this cover page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            California
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   49,800
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    49,800
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            49,800
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            0.1%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            PN
------------====================================================================



                               Page 4 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Farallon Capital Institutional Partners III, L.P.
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page,  however,  is a beneficial  owner only of
                           the securities reported by it on this cover page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            Delaware
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   39,100
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    39,100
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            39,100
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            0.1%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            PN
------------====================================================================



                               Page 5 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Tinicum Partners, L.P.
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page,  however,  is a beneficial  owner only of
                           the securities reported by it on this cover page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            New York
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   16,800
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    16,800
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            16,800
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            0.0%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            PN
------------====================================================================



                               Page 6 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Farallon Capital Offshore Investors II, L.P.
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page,  however,  is a beneficial  owner only of
                           the securities reported by it on this cover page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            Cayman Islands
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   564,717
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    564,717
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            564,717
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            1.1%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            PN
------------====================================================================



                               Page 7 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Farallon Partners, L.L.C.
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page, however, may be deemed a beneficial owner
                           only of the  securities  reported by it on this cover
                           page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            Delaware
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   1,590,817
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    1,590,817
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            1,590,817
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            3.2%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            OO
------------====================================================================



                               Page 8 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Farallon Capital Management, L.L.C.
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page, however, may be deemed a beneficial owner
                           only of the  securities  reported by it on this cover
                           page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            Delaware
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   1,226,683
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    1,226,683
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            1,226,683
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            2.5%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            IA, OO
------------====================================================================



                               Page 9 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Chun R. Ding
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page, however, may be deemed a beneficial owner
                           only of the  securities  reported by it on this cover
                           page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            United States
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   2,817,500
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    2,817,500
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            2,817,500
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            5.7%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            IN
------------====================================================================



                              Page 10 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            William F. Duhamel
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page, however, may be deemed a beneficial owner
                           only of the  securities  reported by it on this cover
                           page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            United States
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   2,817,500
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    2,817,500
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            2,817,500
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                    [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            5.7%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            IN
------------====================================================================



                              Page 11 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Charles E. Ellwein
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page, however, may be deemed a beneficial owner
                           only of the  securities  reported by it on this cover
                           page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            United States
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   2,817,500
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    2,817,500
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            2,817,500
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            5.7%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            IN
------------====================================================================



                              Page 12 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Richard B. Fried
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page, however, may be deemed a beneficial owner
                           only of the  securities  reported by it on this cover
                           page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            United States
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   2,817,500
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    2,817,500
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            2,817,500
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            5.7%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            IN
------------====================================================================



                              Page 13 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Monica R. Landry
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page, however, may be deemed a beneficial owner
                           only of the  securities  reported by it on this cover
                           page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            United States
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   2,817,500
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    2,817,500
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            2,817,500
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            5.7%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            IN
------------====================================================================



                              Page 14 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            William F. Mellin
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page, however, may be deemed a beneficial owner
                           only of the  securities  reported by it on this cover
                           page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            United States
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   2,817,500
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    2,817,500
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            2,817,500
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            5.7%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            IN
------------====================================================================



                              Page 15 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Stephen L. Millham
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page, however, may be deemed a beneficial owner
                           only of the  securities  reported by it on this cover
                           page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            United States
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   2,817,500
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    2,817,500
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            2,817,500
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            5.7%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            IN
------------====================================================================



                              Page 16 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Jason E. Moment
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page, however, may be deemed a beneficial owner
                           only of the  securities  reported by it on this cover
                           page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            United States
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   2,817,500
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    2,817,500
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            2,817,500
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            5.7%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            IN
------------====================================================================



                              Page 17 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Rajiv A. Patel
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page, however, may be deemed a beneficial owner
                           only of the  securities  reported by it on this cover
                           page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            United States
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   2,817,500
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    2,817,500
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            2,817,500
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            5.7%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            IN
------------====================================================================



                              Page 18 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Derek C. Schrier
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page, however, may be deemed a beneficial owner
                           only of the  securities  reported by it on this cover
                           page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            United States
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   2,817,500
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    2,817,500
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            2,817,500
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            5.7%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            IN
------------====================================================================



                              Page 19 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Thomas F. Steyer
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page, however, may be deemed a beneficial owner
                           only of the  securities  reported by it on this cover
                           page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            United States
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   2,817,500
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    2,817,500
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            2,817,500
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            5.7%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            IN
------------====================================================================



                              Page 20 of 28 Pages




                                       13G
===================
CUSIP No. 584688105
===================

------------====================================================================
            NAMES OF REPORTING PERSONS
     1      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

            Mark C. Wehrly
------------====================================================================
            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                               (a)[   ]
                                                               (b)[ X ]**
     2
                   **      The  reporting  persons  making  this  filing hold an
                           aggregate of 2,817,500  Shares,  which is 5.7% of the
                           class of  securities.  The  reporting  person on this
                           cover page, however, may be deemed a beneficial owner
                           only of the  securities  reported by it on this cover
                           page.
------------====================================================================
     3      SEC USE ONLY

------------====================================================================
            CITIZENSHIP OR PLACE OF ORGANIZATION
     4
            United States
------------====================================================================
                                    SOLE VOTING POWER
                             5
         NUMBER OF                  -0-
                        ------------============================================
          SHARES                    SHARED VOTING POWER
       BENEFICIALLY          6
         OWNED BY                   2,817,500
                        ------------============================================
           EACH                     SOLE DISPOSITIVE POWER
                             7
         REPORTING                  -0-
        PERSON WITH     ------------============================================
                                    SHARED DISPOSITIVE POWER
                             8
                                    2,817,500
------------====================================================================
            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     9
            2,817,500
------------====================================================================
            CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
     10     CERTAIN SHARES (See Instructions)                     [   ]

------------====================================================================
            PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     11
            5.7%
------------====================================================================
            TYPE OF REPORTING PERSON (See Instructions)
     12
            IN
------------====================================================================



                              Page 21 of 28 Pages




Item 1.  Issuer
         ------

         (a) Name of Issuer:
             --------------
             The Medicines Company (the "Company")

         (b) Address of Issuer's Principal Executive Offices:
             -----------------------------------------------
             8 Campus Drive, Parsippany, New Jersey 07054

Item 2.  Identity And Background
         -----------------------

         Title Of Class Of Securities And CUSIP Number (Item 2(d) and (e))
         ----------------------------------------------------------------

         This statement  relates to shares of Common Stock, par value $0.001 per
share  (the  "Shares"),  of the  Company.  The  CUSIP  number  of the  Shares is
584688105.

         Name Of  Persons  Filing,  Address  Of  Principal  Business  Office And
         -----------------------------------------------------------------------
         Citizenship (Item 2(a), (b) and (c))
         ------------------------------------

         This statement is filed by the entities and persons  listed below,  all
of whom together are referred to herein as the "Reporting Persons."

         The Farallon Funds
         ------------------

                  (i)      Farallon Capital Partners, L.P., a California limited
                           partnership ("FCP"),  with respect to the Shares held
                           by it;

                  (ii)     Farallon  Capital  Institutional  Partners,  L.P.,  a
                           California limited partnership ("FCIP"), with respect
                           to the Shares held by it;

                  (iii)    Farallon Capital  Institutional  Partners II, L.P., a
                           California  limited  partnership  ("FCIP  II"),  with
                           respect to the Shares held by it;

                  (iv)     Farallon Capital Institutional  Partners III, L.P., a
                           Delaware  limited   partnership  ("FCIP  III"),  with
                           respect to the Shares held by it;

                  (v)      Tinicum   Partners,   L.P.,   a  New   York   limited
                           partnership  ("Tinicum"),  with respect to the Shares
                           held by it; and

                  (vi)     Farallon  Capital  Offshore  Investors  II,  L.P.,  a
                           Cayman Islands  exempted limited  partnership  ("FCOI
                           II"), with respect to the Shares held by it.

         FCP, FCIP, FCIP II, FCIP III, Tinicum and FCOI II are together referred
to herein as the "Farallon Funds."




                              Page 22 of 28 Pages





         The Management Company
         ----------------------

                  (vii)    Farallon  Capital  Management,   L.L.C.,  a  Delaware
                           limited liability company (the "Management Company"),
                           with respect to the Shares held by a certain  account
                           managed  by  the  Management  Company  (the  "Managed
                           Account").

         The Farallon General Partner
         ----------------------------

                  (viii)   Farallon   Partners,   L.L.C.,   a  Delaware  limited
                           liability  company  which is the  general  partner of
                           each of the  Farallon  Funds (the  "Farallon  General
                           Partner"), with respect to the Shares held by each of
                           the Farallon Funds.

         The Farallon Managing Members
         -----------------------------

                  (ix)     The  following  persons who are  managing  members of
                           both the Farallon  General Partner and the Management
                           Company,  with  respect  to the  Shares  held  by the
                           Farallon Funds and the Managed Account:  Chun R. Ding
                           ("Ding"), William F. Duhamel ("Duhamel"),  Charles E.
                           Ellwein  ("Ellwein"),  Richard  B.  Fried  ("Fried"),
                           Monica  R.  Landry  ("Landry"),   William  F.  Mellin
                           ("Mellin"),  Stephen L. Millham ("Millham"), Jason E.
                           Moment ("Moment"), Rajiv A. Patel ("Patel"), Derek C.
                           Schrier ("Schrier"),  Thomas F. Steyer ("Steyer") and
                           Mark C. Wehrly ("Wehrly").

         Ding, Duhamel,  Ellwein, Fried, Landry, Mellin, Millham, Moment, Patel,
Schrier,  Steyer and Wehrly are  together  referred  to herein as the  "Farallon
Individual Reporting Persons."

         The citizenship of each of the Farallon Funds,  the Management  Company
and the  Farallon  General  Partner  is set forth  above.  Each of the  Farallon
Individual  Reporting Persons is a citizen of the United States.  The address of
the principal  business office of each of the Reporting  Persons is c/o Farallon
Capital  Management,  L.L.C.,  One Maritime  Plaza,  Suite 1325,  San Francisco,
California 94111.


Item 3.  If This  Statement  Is  Filed  Pursuant  To  Sections  240.13d-1(b)  or
         -----------------------------------------------------------------------
         240.13d-2(b)  or (c),  Check  Whether  The  Person  Filing Is An Entity
         -----------------------------------------------------------------------
         Specified In (a) - (j):
         -----------------------

         Not Applicable.

         If This Statement Is Filed Pursuant To Section 240.13d-1(c), Check This
         -----------------------------------------------------------------------
         Box. [X]
         ----

Item 4.  Ownership
         ---------



                              Page 23 of 28 Pages




         The  information  required  by Items 4(a) - (c) and set forth in Rows 5
through 11 of the cover page for each  Reporting  Person hereto is  incorporated
herein by reference for each such Reporting Person.

         The Shares reported hereby for the Farallon Funds are owned directly by
the Farallon Funds and those reported by the Management Company on behalf of the
Managed Account are owned directly by the Managed Account.  The Farallon General
Partner,  as general  partner  to the  Farallon  Funds,  may be deemed to be the
beneficial  owner of all such Shares owned by the Farallon Funds. The Management
Company,  as investment adviser to the Managed Account,  may be deemed to be the
beneficial owner of all such Shares owned by the Managed  Account.  The Farallon
Individual  Reporting Persons,  as managing members of both the Farallon General
Partner  and the  Management  Company  with  the  power to  exercise  investment
discretion,  may each be deemed to be the  beneficial  owner of all such  Shares
owned by the  Farallon  Funds and the Managed  Account.  Each of the  Management
Company,  the Farallon  General  Partner and the Farallon  Individual  Reporting
Persons hereby disclaims any beneficial ownership of any such Shares.

Item 5.  Ownership Of Five Percent Or Less Of A Class
         --------------------------------------------

         Not Applicable.

Item 6.  Ownership Of More Than Five Percent On Behalf Of Another Person
         ---------------------------------------------------------------

         Not Applicable.

Item 7.  Identification  And Classification Of The Subsidiary Which Acquired The
         -----------------------------------------------------------------------
         Security Being Reported On By The Parent Holding Company
         --------------------------------------------------------

         Not Applicable.

Item 8.  Identification And Classification Of Members Of The Group
         ---------------------------------------------------------

         The Reporting  Persons are filing this Schedule 13G pursuant to Section
240.13d-1(c). Consistent with Item 2 of the cover page for each Reporting Person
above,  the  Reporting  Persons  neither  disclaim nor affirm the existence of a
group among them.

Item 9.  Notice Of Dissolution Of Group
         ------------------------------

         Not Applicable.

Item 10. Certification
         --------------

         By  signing  below I  certify  that,  to the best of my  knowledge  and
belief, the securities  referred to above were not acquired and are not held for
the purpose of or with the effect of changing or influencing  the control of the
issuer of the  securities  and were not acquired and are not held in  connection
with or as a participant in any transaction having that purpose or effect.



                              Page 24 of 28 Pages




                                   SIGNATURES


         After  reasonable  inquiry and to the best of our knowledge and belief,
the  undersigned  certify that the  information  set forth in this  statement is
true, complete and correct.

Dated:  March 23, 2006


               /s/ Monica R. Landry
               ----------------------------------------
               FARALLON PARTNERS, L.L.C.,
               On its own behalf and
               as the General Partner of
               FARALLON CAPITAL PARTNERS, L.P.,
               FARALLON CAPITAL INSTITUTIONAL PARTNERS, L.P.,
               FARALLON CAPITAL INSTITUTIONAL PARTNERS II, L.P.,
               FARALLON CAPITAL INSTITUTIONAL PARTNERS III, L.P.,
               TINICUM PARTNERS, L.P. and
               FARALLON CAPITAL OFFSHORE INVESTORS II, L.P.
               By Monica R. Landry,
               Managing Member

               /s/ Monica R. Landry
               ----------------------------------------
               FARALLON CAPITAL MANAGEMENT, L.L.C.
               By Monica R. Landry,
               Managing Member

               /s/ Monica R. Landry
               ----------------------------------------
               Monica R. Landry, individually and as attorney-in-fact for
               each of Chun R. Ding, William F. Duhamel, Charles E. Ellwein,
               Richard B. Fried, William F. Mellin, Stephen L. Millham, Jason E.
               Moment, Rajiv A. Patel, Derek C. Schrier, Thomas F. Steyer and
               Mark C. Wehrly

         The Powers of Attorney  executed by Duhamel,  Fried,  Mellin,  Millham,
Steyer and Wehrly  authorizing Landry to sign and file this Schedule 13G on each
person's behalf, which were filed with Amendment No. 2 to the Schedule 13D filed
with the Securities and Exchange  Commission on July 16, 2003, by such Reporting
Persons with respect to the Common Stock of New World  Restaurant  Group,  Inc.,
are hereby  incorporated by reference.  The Powers of Attorney  executed by Ding
and  Schrier  authorizing  Landry  to sign and file  this  Schedule  13G on each
person's behalf, which were filed with Amendment No. 1 to the Schedule 13D filed
with the Securities  and Exchange  Commission on July 2, 2003, by such Reporting
Persons  with respect to the Common Stock of Salix  Pharmaceuticals,  Ltd.,  are
hereby incorporated by reference. The Powers of Attorney executed by Ellwein and
Patel authorizing Landry to sign



                              Page 25 of 28 Pages




and file this  Schedule  13G on each  person's  behalf,  which  were  filed with
Amendment  No. 4 to the  Schedule  13G filed with the  Securities  and  Exchange
Commission  on January 8, 2004,  by such  Reporting  Persons with respect to the
Common Stock of Catalytica  Energy  Systems,  Inc., are hereby  incorporated  by
reference.  The Power of Attorney executed by Moment  authorizing Landry to sign
and file this Schedule 13G on his behalf,  which was filed with the Schedule 13D
filed with the  Securities  and Exchange  Commission on January 9, 2006, by such
Reporting Person with respect to the Common Stock of Vintage Petroleum, Inc., is
hereby incorporated by reference.


























                              Page 26 of 28 Pages





                                  EXHIBIT INDEX

EXHIBIT 1                                Joint Acquisition Statement Pursuant to
                                         Section 240.13d-1(k)





























                              Page 27 of 28 Pages





                                                                       EXHIBIT 1
                                                                              to
                                                                    SCHEDULE 13G

                           JOINT ACQUISITION STATEMENT
                        PURSUANT TO SECTION 240.13d-1(k)

         The undersigned  acknowledge and agree that the foregoing  statement on
Schedule  13G is  filed  on  behalf  of each of the  undersigned  and  that  all
subsequent amendments to this statement on Schedule 13G shall be filed on behalf
of each of the  undersigned  without the  necessity of filing  additional  joint
acquisition   statements.   The  undersigned  acknowledge  that  each  shall  be
responsible for the timely filing of such  amendments,  and for the completeness
and accuracy of the information concerning him, her or it contained therein, but
shall not be responsible  for the  completeness  and accuracy of the information
concerning the other  entities or persons,  except to the extent that he, she or
it knows or has reason to believe that such information is inaccurate.

Dated:  March 23, 2006


               /s/ Monica R. Landry
               ----------------------------------------
               FARALLON PARTNERS, L.L.C.,
               On its own behalf and
               as the General Partner of
               FARALLON CAPITAL PARTNERS, L.P.,
               FARALLON CAPITAL INSTITUTIONAL PARTNERS, L.P.,
               FARALLON CAPITAL INSTITUTIONAL PARTNERS II, L.P.,
               FARALLON CAPITAL INSTITUTIONAL PARTNERS III, L.P.,
               TINICUM PARTNERS, L.P. and
               FARALLON CAPITAL OFFSHORE INVESTORS II, L.P.
               By Monica R. Landry,
               Managing Member

               /s/ Monica R. Landry
               ----------------------------------------
               FARALLON CAPITAL MANAGEMENT, L.L.C.
               By Monica R. Landry,
               Managing Member

               /s/ Monica R. Landry
               ----------------------------------------
               Monica R. Landry, individually and as attorney-in-fact for
               each of Chun R. Ding, William F. Duhamel, Charles E. Ellwein,
               Richard B. Fried, William F. Mellin, Stephen L. Millham, Jason E.
               Moment, Rajiv A. Patel, Derek C. Schrier, Thomas F. Steyer and
               Mark C. Wehrly


                              Page 28 of 28 Pages