SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, DC 20549


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                                  SCHEDULE 13D
                                 (Rule 13d-101)


                 INFORMATION TO BE INCLUDED IN STATEMENTS FILED
                          PURSUANT TO RULE 13d-1(a) AND
               AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(a)
                            (AMENDMENT NO.  2  ) 1
                                          -----


                           Senesco Technologies, Inc.
                           --------------------------
                                (Name of Issuer)


                          Common Stock, $.01 par value
                         ------------------------------
                         (Title of Class of Securities)


                                   817208 40 8
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                                 (CUSIP Number)


Joel Brooks,  303 George Street, Suite  420,  New Brunswick,  New Jersey   08901
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                                 (732-296-8400)
                                 --------------
(Name, Address and Telephone Number of Person Authorized to Receive Notices and
                                Communications)


                                December 31, 2001
                                -----------------
             (Date of Event Which Requires Filing of this Statement)


If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  that is the subject of this  Schedule  13D, and is filing this
schedule  because of Rule  13d-1(e),  13d-1(f) or 13d-1(g),  check the following
box. |_|

Note.  Schedules  filed in paper format shall include a signed original and five
copies of the schedule, including all exhibits.

See Rule 13d-7(b) for other parties to whom copies are to be sent.

                         (Continued on following pages)
                               (Page 1 of 6 Pages)


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1       The remainder of this  cover page shall be  filled  out for a  reporting
person's  initial  filing on this  form with  respect  to the  subject  class of
securities,  and for any subsequent amendment containing information which would
alter the disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 or  otherwise  subject to the  liabilities  of that  section of the Act but
shall be subject to all other provisions of the Act (however, see the Notes).




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    CUSIP No. 817208 40 8          13D                Page 2 of 6 Pages
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  1    NAMES OF REPORTING PERSONS
       I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
       John E. Thompson, Ph.D.
       ------------------------
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  2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*            (a)|_|
                                                                    (b)|_|
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  3    SEC USE ONLY

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  4    SOURCE OF FUNDS *       PF

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  5    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
       ITEM 2(d) or 2 (e)                                          |_|

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  6    CITIZENSHIP OR PLACE OF ORGANIZATION

           Canada
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   NUMBER OF      7  SOLE VOTING POWER              638,667
                                                  ----------
     SHARES      ------------------------------------------------------------

  BENEFICIALLY    8  SHARED VOTING POWER            N/A

    OWNED BY     ------------------------------------------------------------

      EACH        9  SOLE DISPOSITIVE POWER         638,667
                                                  ---------
   REPORTING     ------------------------------------------------------------

  PERSON WITH    10  SHARED DISPOSITIVE POWER       N/A

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  11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

               638,667
              ---------
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  12   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
       CERTAIN SHARES*                                                |_|

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  13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 11              6.35%
                                                                  ---------
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  14   TYPE OF REPORTING PERSON*                                      IN

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                      *SEE INSTRUCTIONS BEFORE FILLING OUT!



 ITEM 1.  SECURITY AND ISSUER.

          The title of the class of equity  securities  to which this  statement
          relates is common  stock,  $.01 par value  (the  "Common  Stock"),  of
          Senesco  Technologies,  Inc., a Delaware  corporation (the "Company").
          The address of the principal  executive  offices of the Company is 303
          George Street, Suite 420, New Brunswick, New Jersey 08901.

 ITEM 2.  IDENTITY AND BACKGROUND.

          (a)  The name of the person filing this statement is John E. Thompson,
               Ph.D.;

          (b)  The business address of Dr. Thompson is c/o Senesco Technologies,
               Inc.,  303 George Street,  Suite 420, New  Brunswick,  New Jersey
               08901;

          (c)  The present principal occupation or employment of Dr. Thompson is
               Executive  Vice-  President  of Research and  Development  of the
               Company;

          (d)  During the last five years,  Dr.  Thompson has not been convicted
               in a criminal proceeding (excluding traffic violations or similar
               misdemeanors);

          (e)  During the last five  years,  Dr.  Thompson  was not a party to a
               civil  proceeding  of  a  judicial  or  administrative   body  of
               competent  jurisdiction as a result of which proceeding it was or
               is subject to a judgment,  decree or final order enjoining future
               violations of, or prohibiting or mandating activities subject to,
               federal or state  securities  laws or finding any violation  with
               respect to such laws; and

          (f)  Dr. Thompson is a citizen of Canada.

 ITEM 3.  SOURCE AND AMOUNT OF FUNDS OR OTHER CONSIDERATION.

          On  October  9,  1998,   Senesco,   Inc.,  a  New  Jersey  corporation
          ("Senesco"),  Nava Leisure USA, Inc., an Idaho  corporation  ("Nava"),
          Nava  Leisure   Acquisition   Corp.,  a  New  Jersey  corporation  and
          wholly-owned   subsidiary   of  Nava   ("NAC"),   and  the   Principal
          Stockholders (as defined therein),  entered into an Agreement and Plan
          of Merger,  providing for the merger of NAC with and into Senesco, and
          the issuance to the  shareholders of Senesco one newly issued share of
          Common Stock of Nava for each share of Common Stock of Senesco whereby
          the  shareholders  of Senesco  acquired  a majority  of the issued and
          outstanding shares of Common Stock of Nava (the "Merger").  The Merger
          was  consummated  on  January  22,  1999,  the  date  upon  which  the
          Certificate  of Merger filed with the  Secretary of State of the State
          of New Jersey was declared  effective.  Upon the  consummation  of the
          Merger,   Senesco  was  the  surviving   corporation  and  remained  a
          subsidiary  of Nava which  changed  its name to Senesco  Technologies,
          Inc., an Idaho corporation ("STI").

          Dr.  Thompson  was a  shareholder  of Senesco and  beneficially  owned
          425,000 shares of Common Stock of Senesco.  As a result of the Merger,
          on January 22, 1999, Dr.  Thompson  received  425,000 shares of Common
          Stock of STI  (formerly  Nava),  consisting of 15.74% of the 2,700,008
          shares of STI Common Stock issued and outstanding.

          On September 7, 1999, STI granted to Dr. Thompson  options to purchase
          40,000  shares of STI Common  Stock,  on a post stock  split  adjusted
          basis (as described  below),  at an exercise  price equal to $3.85 per
          share.  Dr. Thompson  received such options as  consideration  for his
          services  as an  executive  officer  of  STI.  All  such  options  are
          currently vested.

          On September 29, 1999, STI declared a two-for-one  forward stock split
          of its issued and  outstanding  Common  Stock  and,  as a result,  Dr.
          Thompson's  holdings of STI Common Stock  increased to 850,000 shares,
          excluding any options to purchase shares of STI Common Stock.

          On September 30, 1999,  STI merged with and into the Company,  for the
          sole  purpose of  reincorporating  the  corporation  from the State of
          Idaho to the State of Delaware.


                                Page 3 of 6 Pages


 ITEM 4.  PURPOSE OF TRANSACTION.

          Dr.  Thompson  acquired  the 850,000  shares of the  Company's  Common
          Stock, on a post stock split adjusted basis, as a result of the Merger
          as discussed in Item 3 above.

          On December 1, 2001, the Company  granted to Dr.  Thompson  options to
          purchase  80,000 shares of the  Company's  Common Stock at an exercise
          price equal to $2.05 per share,  pursuant to the Company's  1998 Stock
          Incentive  Plan,  as amended.  Dr.  Thompson  received such options as
          consideration for his services as an executive officer of the Company.
          One-third  (1/3) of such  options  became  exercisable  on the date of
          grant,  one-third  (1/3) of such options shall become  exercisable  on
          December 1, 2002,  and  one-third  (1/3) of such options  shall become
          exercisable on December 1, 2003.

          On  December  10,  2001,  Dr.  Thompson  sold  250,000  shares  of the
          Company's  Common  Stock to an  unrelated  third  party  pursuant to a
          private resale agreement.

          On  December  18,  2001,  Dr.  Thompson  gifted  28,000  shares of the
          Company's  Common  Stock for no  consideration  to the  University  of
          Waterloo,  an  educational  institution  in which  neither  he nor any
          member of his family exercises  investment control or possesses voting
          or dispositive power.

          Dr. Thompson may from time to time,  depending upon market conditions,
          the  state of  affairs  of the  Company  and  other  factors,  acquire
          additional  shares  of  Common  Stock  of  the  Company,   subject  to
          applicable  laws and to the  availability  of shares at prices  deemed
          favorable.  Alternatively,  Dr.  Thompson may dispose of shares of the
          Company's  Common  Stock.  Dr.  Thompson will continue to consider his
          equity interests in the Company and he reserves the right to formulate
          such  plans or  proposals,  and to take  such  action,  as he may deem
          appropriate in light of future circumstances.

          Except as set forth  above,  Dr.  Thompson  does not have any  present
          plans or  intentions  which  would  result  in or relate to any of the
          following:

          (a)  The  acquisition  by any person of  additional  securities of the
               Company, or the disposition of securities of the Company;

          (b)  An  extraordinary  corporate  transaction,   such  as  a  merger,
               reorganization or liquidation, involving the Company;

          (c)  A sale or transfer of a material amount of assets of the Company;

          (d)  Any change in the present board of directors or management of the
               Company, including any plans or proposals to change the number or
               terms of  directors  or to fill  any  existing  vacancies  on the
               board;

          (e)  Any  material  change in the present  capitalization  or dividend
               policy of the Company;

          (f)  Any other material change in the Company's  business or corporate
               structure;

          (g)  Changes  in  the  Company's   charter,   bylaws  or   instruments
               corresponding  thereto  or other  actions  which may  impede  the
               acquisition of control of the Company by any person;

          (h)  Causing a class of  securities of the Company to be delisted from
               a national securities exchange or to cease to be authorized to be
               quoted  in  an  inter-dealer  quotation  system  of a  registered
               national securities association;

          (i)  A class of equity securities of the Company becoming eligible for
               termination of registration  pursuant to Section  12(g)(4) of the
               Act; or

          (j)  Any action similar to any of those enumerated above.

                                Page 4 of 6 Pages


 ITEM 5.  INTEREST IN SECURITIES OF THE ISSUER.

          (a)  Dr.  Thompson  beneficially  owns 638,667 shares of the Company's
               Common  Stock,  including  options to purchase  66,667  shares of
               Common Stock exercisable  within 60 days. Dr. Thompson's  638,667
               shares  of  Common  Stock  represents  6.35%  of the  issued  and
               outstanding  shares  of the  Company's  Common  Stock,  based  on
               9,987,187 shares issued and outstanding as of December 31, 2001.

          (b)  Dr.  Thompson has the sole power to vote or to direct the vote of
               all of the 638,667 shares of the Company's Common Stock, assuming
               the exercise of all options.

          (c)  On September 7, 1999, the Company granted to Dr. Thompson options
               to purchase  40,000 shares of the Company's  Common Stock,  at an
               exercise  price equal to $3.85 per share.  One-half (1/2) of such
               options  vested on the date of grant and  one-half  (1/2) of such
               options vested on June 30, 2000.  Such options were issued to Dr.
               Thompson  in  consideration  for  his  services  as an  executive
               officer of the Company.

               On December 1, 2001, the Company granted to Dr. Thompson  options
               to purchase  80,000  shares of the  Company's  Common Stock at an
               exercise  price  equal  to  $2.05  per  share,  pursuant  to  the
               Company's 1998 Stock Incentive Plan, as amended.  One-third (1/3)
               of such options vested on the date of grant,  one-third  (1/3) of
               such  options  shall  become  vested on  December  1,  2002,  and
               one-third  (1/3) of such options  shall become vested on December
               1,  2003.   Such   options   were  issued  to  Dr.   Thompson  in
               consideration  for his  services as an  executive  officer of the
               Company.

               In 2001,  the  percentage  of the issued and  outstanding  Common
               Stock  of the  Company  beneficially  owned by Dr.  Thompson  was
               materially  reduced due to (i) his sale of 250,000  shares of the
               Company's  Common Stock to an unrelated third party, and (ii) the
               Company's  private  placements of 1,142,858 and 665,714 shares of
               its restricted Common Stock, completed in December 2001.

          (d)  No other  person  is known to have the  right to  receive  or the
               power to direct the receipt of  dividends  from,  or the proceeds
               from the sale of, such securities.

          (e)  Not applicable.

 ITEM 6.  CONTRACTS,  ARRANGEMENTS,  UNDERSTANDINGS  OR  RELATIONSHIPS WITH  THE
          ISSUER.

          There  is no  contract,  arrangement,  understanding  or  relationship
          (legal or otherwise) between Dr. Thompson and the Company with respect
          to any  securities  of the  Company,  including  but not  limited  to,
          transfer  of voting of any of the  securities,  finder's  fees,  joint
          ventures,  loan or option arrangements,  puts or calls,  guarantees of
          profits,  division of profits or loss, or the giving or withholding of
          proxies.

 ITEM 7.  MATERIAL TO BE FILED AS EXHIBITS.

          None.


                                Page 5 of 6 Pages


                                    SIGNATURE

     After  reasonable  inquiry and to the best of my  knowledge  and belief,  I
certify that the information  set forth in this statement is true,  complete and
correct.



February 13, 2002                 /s/ John E. Thompson
                                  ------------------------------------------
                                  John E. Thompson, Ph.D., Stockholder


          The original statement shall be signed by each person on whose  behalf
the  statement is filed or his  authorized  representative.  If the statement is
signed on behalf of a person by his  authorized  representative  (other  than an
executive  officer or general  partner of the filing  person),  evidence  of the
representative's  authority to sign on behalf of such person shall be filed with
the  statement,  provided,  however,  that a power of attorney  for this purpose
which is already on file with the Commission may be  incorporated  by reference.
The name and any title of each person who signs the statement  shall be typed or
printed beneath his signature.

          Attention.  Intentional  misstatements or omissions of fact constitute
Federal criminal violations (See 18 U.S.C. 1001).




                                Page 6 of 6 Pages