SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Neotherapeutics Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 640656104 (CUSIP Number) February 1, 2002 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: [ ] Rule 13d-1(b) [X] Rule 13d-1(c) [ ] Rule 13d-1(d) * The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). CUSIP No. 640656104 13G Page 2 of 6 Pages ________________________________________________________________________________ 1. NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON RBC Funds Inc. ________________________________________________________________________________ 2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [_] ________________________________________________________________________________ 3. SEC USE ONLY ________________________________________________________________________________ 4. CITIZENSHIP OR PLACE OF ORGANIZATION The jurisdiction of organization is Canada ________________________________________________________________________________ 5. SOLE VOTING POWER N/A NUMBER OF _________________________________________________________________ SHARES 6. SHARED VOTING POWER BENEFICIALLY OWNED BY EACH 1,150,000 REPORTING _________________________________________________________________ PERSON WITH 7. SOLE DISPOSITIVE POWER N/A _________________________________________________________________ 8. SHARED DISPOSITIVE POWER 1,150,000 ________________________________________________________________________________ 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,150,000 ________________________________________________________________________________ 10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* [_] ________________________________________________________________________________ 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 5.1% ________________________________________________________________________________ 12. TYPE OF REPORTING PERSON* OO ________________________________________________________________________________ *SEE INSTRUCTIONS BEFORE FILLING OUT! Item 1(a) Name of Issuer: Neotherapeutics Inc. Item 1(b) Address of Issuer's Principal Executive Offices: Neotherapeutics Inc. 157 Technology Drive Irvine, CA 92618 (949) 788-6700 Item 2(a) Name of Person Filing: RBC Funds Inc. Item 2(b) Address of Principal Business Office or, if None, Residence: RBC Funds Inc. Royal Trust Tower, P.O. Box 7500, Station A 77 King Street West Toronto, Ontario M5W 1P9 Item 2(a) Citizenship: Canada Item 2(d) Title of Class of Securities: Common Stock Item 2(e) CUSIP Number: 640656104 Item 3. If this statement is filed pursuant to Rules 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a: (a) [_] Broker or dealer registered under Section 15 of the Act (15 U.S.C.78o); (b) [_] Bank as defined in Section 3(a)(6) of the Act (15 U.S.C.78c); (c) [_] Insurance company as defined in Section 3(a)(19) of the Act (15 U.S.C.78c); (d) [_] Investment company registered under Section 8 of the Investment Company Act of 1940 (15 U.S.C.8a-8); (e) [_] An Investment Adviser in accordance with Section 240. 13d-1(b)(1) (ii)(E); (f) [_] An employee benefit plan or endowment fund in accordance with Section 240. 13d-1(b)(1)(ii)(F); (g) [_] A parent holding company or control person in accordance with Section 240. 13d-1(b)(1)(ii)(G); (h) [_] A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813); (i) [_] A church plan that is excluded from the definition of an investment company under Section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C.80a-3); (j) [_] Group, in accordance with Section 240. 13d-1(b)(1)(ii)(J). If this statement is filed pursuant to Section 240 13d-1(c), check this box. [X] Item 4. Ownership. (a) Amount beneficially owned: 1,150,000 (b) Percent of class: 5.1% (c) Number of shares as to which such person has: (i) Sole power to vote or to direct the vote N/A (ii) Shared power to vote or to direct the vote 1,150,000 (iii) Sole power to dispose or to direct the disposition of N/A (iv) Shared power to dispose or to direct the disposition of 1,150,000 Item 5. Ownership of Five Percent or Less of a Class. If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following [X]. Item 6. Ownership of More than Five Percent on Behalf of Another Person. RBC Funds Inc., a wholly-owned subsidiary of Royal Bank Holding Inc., is the manager of accounts and has delegated its investment management duties to RBC Global Investment Management Inc. ("RBC GIM"). RBC GIM is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from, the sale of securities in such account. No such account holds more than five percent of the class. Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company. N/A Item 8. Identification and Classification of Members of the Group. N/A Item 9. Notice of Dissolution of Group. N/A Item 10. Certification. By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of and do not have the effect of changing or influencing the control of the issuer of such securities and were not acquired and are not held in connection with or as a participant in any transaction having such purpose or effect. SIGNATURE After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. February 11, 2002 ------------------------------- (Date) /s/ Mark L. Arthur ------------------------------- (Signature) Mark L. Arthur Chief Investment Officer, RBC Funds Inc. ------------------------------- (Name/Title