Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Ribeill Yves J
 2. Date of Event Requiring Statement (Month/Day/Year)
05/02/2014		 3. Issuer Name and Ticker or Trading Symbol
SCYNEXIS INC [SCYX]
(Last)
(First)
(Middle)
C/O SCYNEXIS, INC.,, 3501 C TRICENTER BOULEVARD		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
President and CEO
 5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

DURHAM, NC 27713		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 16,975
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Common Stock Warrant (right to buy) 01/31/2014 01/30/2019 Common Stock 595 $ 0.2 D  
Series D-2 Preferred Stock 12/11/2013   (1) Common Stock 595 (1) $ (1) D  
Stock Option (right to buy)   (2) 10/21/2014 Common Stock 7,352 $ 20.4 D  
Stock Option (right to buy)   (2) 04/27/2015 Common Stock 7,352 $ 20.4 D  
Stock Option (right to buy)   (2) 04/19/2016 Common Stock 931 $ 20.4 D  
Stock Option (right to buy)   (2) 04/25/2017 Common Stock 3,676 $ 20.4 D  
Stock Option (right to buy)   (2) 04/17/2018 Common Stock 2,941 $ 20.4 D  
Stock Option (right to buy)   (2) 04/22/2019 Common Stock 3,676 $ 25.5 D  
Stock Option (right to buy)   (2) 07/14/2020 Common Stock 2,941 $ 25.91 D  
Stock Option (right to buy)   (2) 04/20/2021 Common Stock 1,960 $ 30.6 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Ribeill Yves J
C/O SCYNEXIS, INC.,
3501 C TRICENTER BOULEVARD
DURHAM, NC 27713		   X     President and CEO  

Signatures

/s/ Eileen Pruette, by power of attorney 05/02/2014
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The Series D-2 Preferred Stock is convertible into Common Stock of the Issuer on a 1-for-20.4 basis at any time at the holder's election, and automatically upon the closing of the Issuer's initial public offering, and has no expiration date.
(2) The option vests and becomes exercisable with respect to 25% of the total number of underlying shares on each the first and the second anniversary of the vesting commencement date and with respect to the remaining 50% of the underlying shares on the third anniversary of the vesting commencement date.

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