Geron Corporation (Nasdaq:GERN) today reported financial results for the three and nine months ended Sept. 30, 2008.

For the third quarter of 2008, the company reported a net loss of $17.2 million, or $(0.22) per share, compared to $12.8 million, or $(0.17) per share, for the comparable 2007 period. Net loss applicable to common stockholders for the first nine months of 2008 was $44.4 million, or $(0.57) per share, compared to $29.3 million, or $(0.40) per share, for the comparable 2007 period. The results of the 2007 period include an unrealized gain of $14.5 million related to changes in fair value of warrants classified as liabilities, and a non-cash expense of $3.7 million related to issuance of warrants in February 2007.

Revenues for the third quarter of 2008 were $367,000, compared to $1.1 million for the comparable 2007 period, which included a milestone payment from Merck & Co., Inc. Revenues for the first nine months of 2008 were $2.3 million, compared to $2.9 million for the comparable 2007 period.

Total operating expenses for the third quarter of 2008 were $18.3 million, compared to $16.5 million for the comparable 2007 period. Research and development expenses for the third quarter of 2008 were $14.2 million, compared to $12.3 million for the comparable 2007 period. Research and development expenses increased primarily as a result of the timing of purchases of GRN163L drug product for clinical trials. General and administrative expenses for the third quarter of 2008 and 2007 were $4.1 million.

Total operating expenses for the first nine months of 2008 were $51.6 million, compared to $51.4 million for the comparable 2007 period. Research and development expenses for the first nine months of 2008 were $39.4 million, compared to $39.6 million for the comparable 2007 period. General and administrative expenses for the first nine months of 2008 were $12.2 million, compared to $11.8 million for the comparable 2007 period. The increase in general and administrative expenses for the first nine months of 2008 primarily reflects increased patent legal costs.

Interest income for the third quarter of 2008 was $1.2 million, compared to $2.8 million for the comparable 2007 period. Interest income for the first nine months of 2008 was $4.5 million, compared to $8.4 million for the comparable 2007 period. Overall interest income has declined as a result of decreased interest rates and lower cash and investment balances period over period.

Third Quarter 2008 Highlights:

• Geron initiated a clinical trial of its telomerase inhibitor drug, GRN163L, in patients with locally recurrent or metastatic breast cancer. The primary objective of the Phase I/II dose escalation study is to determine the safety, maximum tolerated dose (MTD) and objective response rate of GRN163L when administered intravenously in combination with a paclitaxel/bevacizumab regimen in this patient population.
• Geron and Exeter Life Sciences, Inc. merged their interests in Start Licensing, Inc., into ViaGen, Inc. The merger of Start and ViaGen combines the broad intellectual property rights to nuclear transfer cloning technology with in-house highly developed breeding services and expertise in advanced reproductive technologies, particularly in cloning, to provide a one-stop licensing and operating company.
• U.S. Patent No. 7,425,448 was issued to Geron with broad claims to cardiomyocytes derived from human embryonic stem cells (hESCs). The patent runs until April 2025 (subject to any patent term extension that may be available). Geron’s GRNCM1 program is developing hESC-derived cardiomyocytes for the treatment of heart disease.

Conference Call

At 8:00 a.m. PDT/11:00 a.m. EDT on Friday, October 31, Thomas B. Okarma, Ph.D., M.D., Geron’s chief executive officer, and David L. Greenwood, Geron’s chief financial officer, will host a conference call to discuss the company’s third quarter and year-to-date results.

Participants can access the conference call via telephone by dialing 866-543-6411 (U.S.) or 617-213-8900 (international). The passcode is 57512982. A live audio-only Webcast is also available through a link that is posted on the events page in the Investor Relations section of Geron’s Website at http://www.geron.com. The audio Web broadcast of the conference call will be available for replay through Nov. 30, 2008.

Geron is a biopharmaceutical company that is developing first-in-class therapeutic products for the treatment of cancer and chronic degenerative diseases, including spinal cord injury, heart failure and diabetes. The products are based on our core expertise in telomerase and human embryonic stem cells. For more information, visit www.geron.com.

This news release may contain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Investors are cautioned that statements in this press release regarding potential applications of Geron’s technologies constitute forward-looking statements that involve risks and uncertainties, including, without limitation, risks inherent in the development and commercialization of potential products, uncertainty of clinical trial results or regulatory approvals or clearances, need for future capital, dependence upon collaborators and maintenance of our intellectual property rights. Actual results may differ materially from the results anticipated in these forward-looking statements. Additional information on potential factors that could affect our results and other risks and uncertainties are detailed from time to time in Geron’s periodic reports, including the quarterly report on Form 10-Q for the quarter ended June 30, 2008.

Contacts:

Geron Corporation
Anna Krassowska, 650-473-7765
Investor and Media Relations
info@geron.com