Looking at options trading activity among components of the Russell 3000 index, there is noteworthy activity today in Axsome Therapeutics Inc (AXSM), where a total volume of 2,556 contracts has been traded thus far today, a contract volume which is representative of approximately 255,600 underlying shares (given that every 1 contract represents 100 underlying shares). That number works out to 82.6% of AXSM's average daily trading volume over the past month, of 309,475 shares..