Federal Reserve meeting minutes indicated that the central bank desired to proceed very cautiously with its tapering program.  The market closed mixed with the Dow losing 68 points to 16,462. Nasdaq rose 12 points to 4165. 

On the upside 

A Seeking Alpha contributor expects Athersys (Nasdaq: ATHX) to continue climbing.

Maxim lifted its price target on Galena Biopharma (Nasdaq: GALE) from $6 to $9 after the biopharmaceutical enrolled its first patient in a Phase 2 trial for the ovarian cancer treatment GALE-301.

Apollo Education (Nasdaq: APOL) reported lower first quarter earnings that beat analyst expectations and raised its full year revenue outlook.

On the downside

Investors locked in profits on FuelCell Energy (Nasdaq: FCEL). 

Profit taking weighed down shares of Ballard Power Systems (Nasdaq: BLDP).

Investors took profits on Gogo (Nasdaq: GOGO).

In the broad market, declining issues outpaced advancers by a margin of 9 to 7 on the NYSE and by nearly 10 to 9 on Nasdaq. The broader S&P 500 held steady at 1837. Bitcoin lost $25.60 or 2.85% to $897.40.