UNITED STATES 
                  SECURITIES AND EXCHANGE COMMISSION 
                        Washington, D.C. 20549 
                                    
                                    
                             SCHEDULE 13G 
                                    
               Under the Securities Exchange Act of 1934 
                                    
                                    
                          (Amendment No. 2)* 
                                    
                                    
                      Express Scripts, Incorporated 
                             (Name of Issuer) 
                                      
                               Common Stock 
                      (Title of Class of Securities) 
                                      
                                302182100 
                              (CUSIP Number) 
                                    
                            December 31, 2004 
         (Date of Event Which Requires Filing of this Statement) 
                                    
                                    
Check the appropriate box to designate the rule pursuant to which this 
Schedule is filed: 
[X] Rule 13d-1(b) 
[ ] Rule 13d-1(c) 
[ ] Rule 13d-1(d) 
 
 
*The remainder of this cover page shall be filled out for a reporting 
person's initial filing on this form with respect to the subject class 
of securities, and for any subsequent amendment containing information 
which would alter the disclosures provided in a prior cover page. 
 
The information required in the remainder of this cover page shall not 
be deemed to be "filed" for the purpose of Section 18 of the Securities 
Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of 
that section of the Act but shall be subject to all other provisions of 
the Act (however, see the Notes). 
                                    


















CUSIP: 302182100                                                Page 1 of 7 

                                    
 1   NAMES OF REPORTING PERSONS 
     I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY) 
     Capital Research and Management Company 
     95-1411037 
      
 2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE          
     INSTRUCTIONS)                                                 (a)     
                                                                      
                                                                    (b)     
 3   SEC USE ONLY 
      
      
 4   CITIZENSHIP OR PLACE OF ORGANIZATION 
      
     Delaware 

             5   SOLE VOTING POWER 
                   
                  NONE 

       
             6   SHARED VOTING POWER 
 NUMBER OF         
   SHARES         NONE 
BENEFICIALL        
 Y OWNED BY 
             7   SOLE DISPOSITIVE POWER 
    EACH           
 REPORTING        10,156,000 
   PERSON 
   WITH: 
             8   SHARED DISPOSITIVE POWER 
                   
                  NONE 
                   
 9   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 
      
     10,156,000     Beneficial ownership disclaimed pursuant to Rule 13d-4 



 10  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES 
     (SEE INSTRUCTIONS) 
      
      
 11  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 
      
     13.4% 

 12  TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) 
      
     IA   







CUSIP: 302182100                                                Page 2 of 7 
 
 
 

                                    
 1   NAMES OF REPORTING PERSONS 
     I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY) 
     The Growth Fund of America, Inc. 
     52-0792143 
      
 2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE          
     INSTRUCTIONS)                                                 (a)     
                                                                      
                                                                    (b)     
 3   SEC USE ONLY 
      
      
 4   CITIZENSHIP OR PLACE OF ORGANIZATION 
      
     Maryland 

             5   SOLE VOTING POWER 
                   
                  4,710,000 

       
             6   SHARED VOTING POWER 
 NUMBER OF         
   SHARES         NONE 
BENEFICIALL        
 Y OWNED BY 
             7   SOLE DISPOSITIVE POWER 
    EACH           
 REPORTING        NONE 
   PERSON 
   WITH: 
             8   SHARED DISPOSITIVE POWER 
                   
                  NONE 
                   
 9   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 
      
     4,710,000       



 10  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES 
     (SEE INSTRUCTIONS) 
      
      
 11  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 
      
     6.2% 

 12  TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) 
      
     IV   

 




CUSIP: 302182100                                                Page 3 of 7 
 
 
 

                  SECURITIES AND EXCHANGE COMMISSION 
                         Washington, DC 20549 
                                    
                             Schedule 13G 
               Under the Securities Exchange Act of 1934 
                                    
                                    
Amendment No. 2 
 
Item 1(a)     Name of Issuer: 
       Express Scripts, Incorporated 
 
Item 1(b)     Address of Issuer's Principal Executive Offices: 
       13900 Riverport Dr. 
       Mayland Heights, MO 63043 
        
Item 2(a)     Name of Person(s) Filing: 
       Capital Research and Management Company and The Growth Fund of 
       America, Inc. 
        
Item 2(b)     Address of Principal Business Office or, if none, 
       Residence: 
       333 South Hope Street 
       Los Angeles, CA  90071 
        
Item 2(c)     Citizenship:   N/A 
        
Item 2(d)     Title of Class of Securities: 
       Common Stock 
        
Item 2(e)     CUSIP Number: 
       302182100 
        
Item 3     If this statement is filed pursuant to sections 240.13d-1(b) 
       or 240.13d-2(b) or (c), check whether the person filing is a:  
       (d)     [X]     Investment company registered under section 8 
            of the Investment Company Act of 1940 (15 U.S.C. 80a-8). 
       (e)      [X]     An investment adviser in accordance with 
            section 240.13d-1(b)(1)(ii)(E). 
        
Item 4     Ownership 
        
       Provide the following information regarding the aggregate 
       number and percentage of the class of securities of the issuer 
       identified in Item 1. 
        
       See pages 2 and 3 
        
       (a)    Amount beneficially owned: 
       (b)    Percent of class: 
       (c)    Number of shares as to which the person has: 
       (i)    Sole power to vote or to direct the vote: 
       (ii)   Shared power to vote or to direct the vote: 
       (iii)  Sole power to dispose or to direct the disposition of: 
       (iv)   Shared power to dispose or to direct the disposition of: 
        


CUSIP: 302182100                                                Page 4 of 7 
 
 
 

                                    
       Capital Research and Management Company, an investment adviser 
       registered under Section 203 of the Investment Advisers Act of 
       1940 is deemed to be the beneficial owner of 10,156,000 shares 
       or 13.4% of the 75,984,000 shares of Common Stock believed to 
       be outstanding as a result of acting as investment adviser to 
       various investment companies registered under Section 8 of the 
       Investment Company Act of 1940. 
        
       The Growth Fund of America, Inc., an investment company 
       registered under the Investment Company Act of 1940, which is 
       advised by Capital Research and Management Company, is the 
       beneficial owner of 4,710,000 shares or 6.2% of the 75,984,000 
       shares of Common Stock believed to be outstanding. 
        
Item 5     Ownership of Five Percent or Less of a Class.  If this 
       statement is being filed to report the fact that as of the date 
       hereof the reporting person has ceased to be the beneficial 
       owner of more than five percent of the class of securities, 
       check the following: [ ] 
        
Item 6     Ownership of More than Five Percent on Behalf of Another 
       Person: N/A 
        
Item 7     Identification and Classification of the Subsidiary Which 
       Acquired the Security Being Reported on By the Parent Holding 
       Company or Control Person.: N/A 
        
Item 8     Identification and Classification of Members of the Group:  
       N/A 
        
Item 9     Notice of Dissolution of Group:  N/A 
        
Item 10     Certification 
        
       By signing below, I certify that, to the best of my knowledge 
       and belief, the securities referred to above were acquired and 
       are held in the ordinary course of business and were not 
       acquired and are not held for the purpose of or with the effect 
       of changing or influencing the control of the issuer of the 
       securities and were not acquired and are not held in connection 
       with or as a participant in any transaction having that purpose 
       or effect. 
        
     Signature 
        
       After reasonable inquiry and to the best of my knowledge and 
       belief, I certify that the information set forth in this 
       statement is true, complete and correct. 
 
 
        Date:          February 9, 2005 
                        
        Signature:     *Paul G. Haaga, Jr. 
        Name/Title:    Paul G. Haaga, Jr., Executive Vice 
                       President 
                       Capital Research and Management Company 
 

CUSIP: 302182100                                                Page 5 of 7 
 

                                    
        Date:          February 9, 2005 
                        
        Signature:     *Paul G. Haaga, Jr. 
        Name/Title:    Paul G. Haaga, Jr., Senior Vice President 
                       The Growth Fund of America, Inc. 
 
        
        
        *By    /s/ James P. Ryan 
               James P. Ryan 
               Attorney-in-fact 
        
               Signed pursuant to a Power of Attorney dated January 10, 
               2005 included as an Exhibit to Schedule 13G filed with 
               the Securities and Exchange Commission by Capital 
               Research and Management Company on February 4, 2005 with 
               respect to Advanced Energy Industries. 









































CUSIP: 302182100                                                Page 6 of 7 
 

                               AGREEMENT 
                                    
                            Los Angeles, CA 
                           February 9, 2005 
 
  Capital Research and Management Company ("CRMC") and The Growth Fund 
of America, Inc. ("GFA") hereby agree to file a joint statement on 
Schedule 13G under the Securities Exchange Act of 1934 (the "Act") in 
connection with their beneficial ownership of Common Stock issued by 
Express Scripts, Incorporated. 
   
  CRMC and GFA state that they are each entitled to individually use 
Schedule 13G pursuant to Rule 13d-1(c) of the Act. 
   
  CRMC and GFA are each responsible for the timely filing of the 
statement and any amendments thereto, and for the completeness and 
accuracy of the information concerning each of them contained therein 
but are not responsible for the completeness or accuracy of the 
information concerning the others. 
   
   
   
                 CAPITAL RESEARCH AND MANAGEMENT COMPANY 
                  
                 BY:              *Paul G. Haaga, Jr. 
                                  Paul G. Haaga, Jr., Executive 
                                   Vice President 
                                   Capital Research and Management 
                                   Company 
 
 
                 THE GROWTH FUND OF AMERICA, INC. 
                  
                 BY:              *Paul G. Haaga, Jr. 
                                  Paul G. Haaga, Jr., Senior Vice 
                                   President 
                                   The Growth Fund of America, 
                                   Inc. 
 
 
*By  /s/ James P. Ryan 
     James P. Ryan 
     Attorney-in-fact 
      
     Signed pursuant to a Power of Attorney dated January 10, 2005 
     included as an Exhibit to Schedule 13G filed with the Securities 
     and Exchange Commission by Capital Research and Management Company 
     on February 4, 2005 with respect to Advanced Energy Industries. 
      












CUSIP: 302182100                                                Page 7 of 7