SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 13G
Under the Securities Exchange Act of 1934
(Amendment No.3)
ALNYLAM PHARMACEUTICALS, INC.
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(Name of issuer)
COMMON STOCK, $0.001 PAR VALUE PER SHARE
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(Title of class of Securities)
02043Q107
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(CUSIP Number)
14 FEBRUARY 2011
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(Date of Event which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which
this Schedule is filed:
[ ] Rule 13d-l(b)
[(] Rule 13d-l(c)
[ ] Rule 13d-l(d)
*The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class
of securities, and for any subsequent amendment containing information
which would alter the disclosures provided in a prior cover page.
The information required on the remainder of this cover page shall
not be deemed "filed" for the purpose of Section 18 of the
Securities Exchange Act of 1934 ("Act") or otherwise subject
to the liabilities of that section of the Act but shall be subject
to all other provisions of the Act (however, see the Notes).
CUSIP NO. 02043Q107 Page 2 of 6 Pages
1. NAME OF REPORTING PERSON
EASTERN CAPITAL LIMITED
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
3. SEC USE ONLY
4. CITIZENSHIP OR PLACE OF ORGANIZATION
CAYMAN ISLANDS
NUMBER OF
5. SOLE VOTING POWER -0-
SHARES
BENEFICIALLY
6. SHARED VOTING POWER 3,783,179
OWNED BY
EACH
7. SOLE DISPOSITIVE POWER -0-
REPORTING
PERSON
8. SHARED DISPOSITIVE POWER 3,783,179
WITH
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
3,783,179 shares
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) [ ]
EXCLUDES CERTAIN SHARES*
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
9.0%
12. TYPE OF REPORTING PERSON*
CO
CUSIP NO. 02043Q107 Page 3 of 6 Pages
1. NAME OF REPORTING PERSON
KENNETH B. DART
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
3. SEC USE ONLY
4. CITIZENSHIP OR PLACE OF ORGANIZATION
CAYMAN ISLANDS
NUMBER OF
5. SOLE VOTING POWER -0-
SHARES
BENEFICIALLY
6. SHARED VOTING POWER 3,783,179
OWNED BY
EACH
7. SOLE DISPOSITIVE POWER -0-
REPORTING
PERSON
8. SHARED DISPOSITIVE POWER 3,783,179
WITH
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
3,783,179 shares
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) [ ]
EXCLUDES CERTAIN SHARES*
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
9.0%
12. TYPE OF REPORTING PERSON*
IN
CUSIP No. 02043Q107 Page 4 of 6 Pages
ITEM l(a). NAME OF ISSUER:
ALNYLAM PHARMACEUTICALS, INC.
ITEM l(b). ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:
300 THIRD STREET,
CAMBRIDGE, MASSACHUSETTS 02142
ITEM 2(a). NAME OF PERSON FILING:
1) EASTERN CAPITAL LIMITED
Eastern Capital Limited is a direct wholly owned
subsidiary of Portfolio Services Ltd., a Cayman Islands Company.
2) KENNETH B. DART
Mr. Dart is the beneficial owner of all of the outstanding
shares of Portfolio Services Ltd., which in turns owns
all the outstanding shares of Eastern Capital Limited.
ITEM 2(b). ADDRESS OF PRINCIPAL OFFICE:
1) P.O. BOX 31363
Grand Cayman KY1-1206 CAYMAN ISLANDS
2) P.O. BOX 31300
Grand Cayman KY1-1206 CAYMAN ISLANDS
ITEM 2(c). CITIZENSHIP:
1) Cayman Islands
2) Belize
ITEM 2(d). TITLE OF CLASS OF SECURITIES:
Common Stock $0.001 par value per share
ITEM 2(e). CUSIP NUMBER: 02043Q107
ITEM 3. Not Applicable.
CUSIP NO. 02043Q107 Page 5 of 6 pages
ITEM 4. OWNERSHIP
As of the date of this filing, Eastern Capital Limited
and Mr. Dart beneficially own in the aggregate the following:
(a) Amount Beneficially owned: 3,783,179
(b) Percent of Class: 9.0%
(c) Number of shares as to which the person has:
(i) sole power to vote or to direct the vote: -0-
(ii) shared power to vote or to direct the vote: 3,783,179
(iii)sole power to dispose of or to direct the disposition of:
-0-
(iv) shared power to dispose of or to direct the disposition of:
3,783,179
ITEM 5. OWNERSHIP OF 5 PERCENT OR LESS OF A CLASS: [ ]
ITEM 6. OWNERSHIP OF MORE THAN 5 PERCENT ON BEHALF OF ANOTHER PERSON:
Not Applicable
ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY
WHICH ACQUIRED THE SECURITY BEING REPORTED ON BY THE
PARENT HOLDING COMPANY OR CONTROL PERSON. Not applicable
CUSIP NO. 02043Q107 Page 6 of 6 pages
ITEM 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.
Not applicable.
ITEM 9. NOTICE OF DISSOLUTION OF GROUP. Not applicable.
ITEM 10. CERTIFICATION.
By signing below I certify that, to the best of my knowledge
and belief, the securities referred to above were not acquired and
are not held for the purpose of or with the effect of changing or
influencing the control of the issuer of the securities and were
not acquired and are not held in connection with or as a participant
in any transaction having that purpose or effect.
SIGNATURE.
After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement
is true, complete and correct.
EASTERN CAPITAL LIMITED
BY: Kenneth B. Dart, Director
14 FEBRUARY 2011
KENNETH B. DART
14 FEBRUARY 2011
1