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If the form is filed by more than one reporting person, see Instruction 5(b)(v). |
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Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). |
(1) |
The shares will convert into Common Stock immediately prior to the closing of the Issuer's initial public offering. The shares do not have an expiration date. |
(2) |
Reflects a 1-for-11 reverse stock split of the Issuer's outstanding securities effected prior to the effectiveness of the Issuer's S-1 Registration Statement. |
(3) |
Each share of Series A Preferred Stock will automatically convert on a 1-to-1.147541 basis into Common Stock immediately prior to the closing of the Issuer's initial public offering. |
(4) |
Represents an aggregate of 241,743 shares of Series A Preferred Stock held by Venrock Associates IV, L.P. ("VA4"), 49,299 shares of Series A Preferred Stock held by Venrock Partners, L.P. ("VP") and 5,939 shares of Series A Preferred Stock held by Venrock Entrepreneurs Fund IV, L.P. ("VEF4"). The sole general partner of VA4 is Venrock Management IV, LLC ("VM4"). The sole general partner of VP is Venrock Partners Management, LLC ("VPM"). The sole general partner of VEF4 is VEF Management IV, LLC ("VEFM4"). Bryan E. Roberts is a member of each of VM4, VPM and VEFM4 and may be deemed to beneficially own all shares held by VA4, VP and VEF4. Each of Dr. Roberts and VM4, VPM and VEFM4 disclaim beneficial ownership over all shares held by VA4, VP and VEF4, except to the extent of their indirect pecuniary interests therein. |
(5) |
Each share of Series B Preferred Stock will automatically convert on a 1-to-1.328671 basis into Common Stock immediately prior to the closing of the Issuer's initial public offering. |
(6) |
Represents an aggregate of 181,881 shares of Series B Preferred Stock held by VA4, 37,091 shares of Series B Preferred Stock held by VP and 4,468 shares of Series B Preferred Stock held by VEF4. The sole general partner of VA4 is VM4. The sole general partner of VP is VPM. The sole general partner of VEF4 is VEFM4. Bryan E. Roberts is a member of each of VM4, VPM and VEFM4 and may be deemed to beneficially own all shares held by VA4, VP and VEF4. Each of Dr. Roberts and VM4, VPM and VEFM4 disclaim beneficial ownership over all shares held by VA4, VP and VEF4, except to the extent of their indirect pecuniary interests therein. |
(7) |
Each share of Series C Preferred Stock will automatically convert on a 1-to-1 basis into Common Stock immediately prior to the closing of the Issuer's initial public offering. |
(8) |
Represents an aggregate of 590,861 shares of Series C Preferred Stock held by VA4, 120,495 shares of Series C Preferred Stock held by VP and 14,517 shares of Series C Preferred Stock held by VEF4. The sole general partner of VA4 is VM4. The sole general partner of VP is VPM. The sole general partner of VEF4 is VEFM4. Bryan E. Roberts is a member of each of VM4, VPM and VEFM4 and may be deemed to beneficially own all shares held by VA4, VP and VEF4. Each of Dr. Roberts and VM4, VPM and VEFM4 disclaim beneficial ownership over all shares held by VA4, VP and VEF4, except to the extent of their indirect pecuniary interests therein. |
(9) |
Each share of Series D Preferred Stock will automatically convert on a 1-to-1 basis into Common Stock immediately prior to the closing of the Issuer's initial public offering. |
(10) |
Represents an aggregate of 311,692 shares of Series D Preferred Stock held by VA4, 63,563 shares of Series D Preferred Stock held by VP and 7,658 shares of Series D Preferred Stock held by VEF4. The sole general partner of VA4 is VM4. The sole general partner of VP is VPM. The sole general partner of VEF4 is VEFM4. Bryan E. Roberts is a member of each of VM4, VPM and VEFM4 and may be deemed to beneficially own all shares held by VA4, VP and VEF4. Each of Dr. Roberts and VM4, VPM and VEFM4 disclaim beneficial ownership over all shares held by VA4, VP and VEF4, except to the extent of their indirect pecuniary interests therein. |