Definitive Additional Materials





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*** Exercise Your Right to Vote ***

Notice of Meeting and Important Notice Regarding the Availability of Proxy Materials for the

Shareholder Meeting to Be Held on March 6, 2012.





Meeting Information            


   HOLOGIC, INC.    Meeting Type:     Annual Meeting


For holders as of:



  January 13, 2012

      Date:      March 6, 2012     Time: 8:30 AM EST


Location:      Hologic, Inc.


   35 Crosby Drive


   Bedford, MA 01730


To obtain directions to the meeting,

please contact Deborah Gordon at (781) 999-7716











You are receiving this communication because you hold shares in the above named company.


    This is not a ballot. You cannot use this notice to vote these shares. This communication presents only an overview of the more complete proxy materials that are available to you on the Internet. You may view the proxy materials online at or easily request a paper copy (see reverse side).
    We encourage you to access and review all of the important information contained in the proxy materials before voting.
    See the reverse side of this notice to obtain proxy materials and voting instructions.



  Before You Vote 


How to Access the Proxy Materials



      Proxy Materials Available to VIEW or RECEIVE:    




  How to View Online:


  Have the information that is printed in the box marked by the arrow   LOGO   (located on the following   page) and visit:


  How to Request and Receive a PAPER or E-MAIL Copy:


  If you want to receive a paper or e-mail copy of these documents, you must request one. There is NO charge for requesting a

  copy. Please choose one of the following methods to make your request:


                                 1) BY INTERNET:

                                 2) BY TELEPHONE:     1-800-579-1639

                                 3) BY E-MAIL*:   


* If requesting materials by e-mail, please send a blank e-mail with the information that is printed in the box marked by the arrow   LOGO    (located on the following page) in the subject line.


Requests, instructions and other inquiries sent to this e-mail address will NOT be forwarded to your investment advisor. Please make the request as instructed above on or before February 21, 2012 to facilitate timely delivery.






  How To Vote 


Please Choose One of the Following Voting Methods






  Vote In Person: Many shareholder meetings have attendance requirements including, but not limited to, the possession of an attendance ticket issued by the entity holding the meeting. Please check the meeting materials for any special requirements for meeting attendance. At the meeting, you will need to request a ballot to vote these shares.


  Vote By Internet: To vote now by Internet, go to Have the information that is printed in the box marked by the arrow   LOGO    available and follow the instructions.


  Vote By Mail: You can vote by mail by requesting a paper copy of the materials, which will include a proxy card.


Voting  Items          


The Board of Directors recommends you vote FOR all the listed nominees:



1.      Election of Directors





        01)    Robert A. Cascella

  06)    Lawrence M. Levy   

        02)    Glenn P. Muir

  07)    Christiana Stamoulis   

        03)    David R. LaVance, Jr.

  08)    Elaine S. Ullian   

        04)    Sally W. Crawford

  09)    Wayne Wilson   

        05)    Nancy L. Leaming

The Board of Directors recommends you vote FOR proposals 2-4:   

2.          To approve, on an advisory basis, the compensation of the named executive officers, as disclosed in the Company’s Proxy Statement for the 2012 Annual Meeting of Stockholders pursuant to the compensation disclosure rules of the Securities and Exchange Commission, including the Compensation Discussion and Analysis, the 2011 Summary Compensation Table and the other related tables and disclosure.


3.          To approve the Hologic, Inc. 2012 Employee Stock Purchase Plan.


4.          Ratification of the appointment of Ernst & Young LLP as the Company’s independent registered public accounting firm.


NOTE: Such other business as may properly come before the meeting or any adjournment thereof.