SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                  Schedule 13G

                    Under the Securities Exchange Act of 1934

                               (Amendment No. 3)*


                   Integra LifeSciences Holdings Corporation
                                (Name of Issuer)


                          Common stock, $.01 par value
                         (Title of Class of Securities)

                                    457985208
                                 (CUSIP Number)

                                December 31, 2005
             (Date of Event Which Requires Filing of this Statement)


Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

[ ]   Rule 13d-1(b)
[ ]   Rule 13d-1(c)
[X]   Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).





                                                              Page 2 of 10 Pages


---------------------
CUSIP No.   457985208                13G
---------------------
------- -----------------------------------------------------------------------
1       NAME OF REPORTING PERSON: Richard E. Caruso, Ph.D.
        I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (entities only):
------- -----------------------------------------------------------------------
2       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
        (a) |X|
        (b) |_|
------- -----------------------------------------------------------------------
3       SEC USE ONLY

------- -----------------------------------------------------------------------
4       CITIZENSHIP OR PLACE OF ORGANIZATION

        United States
-------------------------------------------- ---- -----------------------------
                                             5    SOLE VOTING POWER
                 NUMBER OF
                                                  85,624 shares*
                  SHARES
                                             ---- -----------------------------
               BENEFICIALLY                  6    SHARED VOTING POWER

                 OWNED BY                         7,114,543*
                                             ---- -----------------------------
                                             7    SOLE DISPOSITIVE POWER
                   EACH
                                                  85,624*
             REPORTING PERSON                ---- -----------------------------
                                             8    SHARED DISPOSITIVE POWER
                   WITH:
                                                  7,114,543*
------- -----------------------------------------------------------------------
9       AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

        7,200,167 shares*
------- -----------------------------------------------------------------------
10      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
         (See Instructions)

------- -----------------------------------------------------------------------
11      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

        25.47%*
------- -----------------------------------------------------------------------
12      TYPE OF REPORTING PERSON (See Instructions)

        IN
------- -----------------------------------------------------------------------

*Includes 85,000 shares of common stock that may be acquired upon exercise of
options as of or within 60 days of February 1, 2006. Dr. Caruso disclaims
beneficial ownership of the shares owned by Tru St Partnership LP and Provco
Leasing Corporation as described in this Schedule 13G (Amendment No. 3) except
to the extent of his pecuniary interest therein.


                                                              Page 3 of 10 Pages

---------------------
CUSIP No.   457985208                 13G
---------------------
------- -----------------------------------------------------------------------
1       NAME OF REPORTING PERSON:  Tru St Partnership LP
        I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (entities only):
------- -----------------------------------------------------------------------
2       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
        (a) |X|
        (b) |_|
------- -----------------------------------------------------------------------
3       SEC USE ONLY

------- -----------------------------------------------------------------------
4       CITIZENSHIP OR PLACE OF ORGANIZATION

        Pennsylvania
-------------------------------------------- ---- -----------------------------
                                             5    SOLE VOTING POWER
                 NUMBER OF
                                                  0
                  SHARES
                                             ---- -----------------------------
               BENEFICIALLY                  6    SHARED VOTING POWER

                 OWNED BY                         7,091,205 shares
                                             ---- -----------------------------
                                             7    SOLE DISPOSITIVE POWER
                   EACH
                                                  0
             REPORTING PERSON                ---- -----------------------------
                                             8    SHARED DISPOSITIVE POWER
                   WITH:
                                                  7,091,205 shares
------- -----------------------------------------------------------------------
9       AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

        7,091,205 shares
------- -----------------------------------------------------------------------
10      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
         (See Instructions)

------- -----------------------------------------------------------------------
11      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

        25.09%
------- -----------------------------------------------------------------------
12      TYPE OF REPORTING PERSON (See Instructions)

        PN
------- -----------------------------------------------------------------------




                                                              Page 4 of 10 Pages



---------------------
CUSIP No.   457985208                13G
---------------------
------- -----------------------------------------------------------------------
1       NAME OF REPORTING PERSON:  Provco Leasing Corporation
        I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (entities only):
------- -----------------------------------------------------------------------
2       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
        (a) |X|
        (b) |_|
------- -----------------------------------------------------------------------
3       SEC USE ONLY
------- -----------------------------------------------------------------------
4       CITIZENSHIP OR PLACE OF ORGANIZATION

        Delaware
-------------------------------------------- ---- -----------------------------
                                             5    SOLE VOTING POWER
                 NUMBER OF
                                                  0
                  SHARES
                                             ---- -----------------------------
               BENEFICIALLY                  6    SHARED VOTING POWER

                 OWNED BY                         7,114,543
                                             ---- -----------------------------
                                             7    SOLE DISPOSITIVE POWER
                   EACH
                                                  0
             REPORTING PERSON                ---- -----------------------------
                                             8    SHARED DISPOSITIVE POWER
                   WITH:
                                                  7,114,543 shares
------- -----------------------------------------------------------------------
9       AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

        7,114,543 shares
------- -----------------------------------------------------------------------
10      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
         (See Instructions)

------- -----------------------------------------------------------------------
11      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

        25.17%
------- -----------------------------------------------------------------------
12      TYPE OF REPORTING PERSON (See Instructions)

        CO
------- -----------------------------------------------------------------------



                                                              Page 5 of 10 Pages

Item 1.

         (a) Name of Issuer:  Integra LifeSciences Holdings Corporation

         (b) Address of Issuer's Principal Executive Offices:  311 Enterprise
             Drive, Plainsboro, New Jersey  08536

Item 2.

         (a) Name of Person Filing: See (c) below.

         (b) Address of Principal Business Office or, if none, Residence: See
             (c) below.

         (c) Citizenship:

                  Richard E. Caruso Ph.D.
                  Building Two, Suite 106,
                  919 Conestoga Road,
                  Rosemount, Pennsylvania 19010
                  United States citizen

                  Tru St Partnership LP
                  Building Two, Suite 106,
                  919 Conestoga Road,
                  Rosemount, Pennsylvania 19010
                  Pennsylvania limited partnership

                  Provco Leasing Corporation
                  209B Baynard Building
                  3411 Silverside Road
                  Wilmington, DE  19810
                  Delaware corporation

         (d) Title of Class of Securities: common stock, $.01 par value.

         (e) CUSIP Number: 457985208

Item 3.           Not applicable.

Item 4.           Ownership: Provide the following information regarding the
                  aggregate number and percentage of the class of securities of
                  the issuer identified in Item 1.

                  (a) Amount beneficially owned: As of December 31, 2005, Dr.
                      Caruso may be deemed the beneficial owner of 7,200,167
                      shares of common stock. He individually holds 624 shares
                      and holds options to purchase 85,000 shares of common
                      stock that are exercisable within 60 days of February 1,
                      2006. Tru St Partnership LP ("Tru St") may be deemed the
                      beneficial owner of 7,091,205 shares of common stock. Dr.
                      Caruso is the president and sole director of Provco
                      Leasing Corporation (`Provco Leasing"). Provco Leasing is
                      the corporate general partner of Tru St. Provco Leasing is
                      also the beneficial owner of 23,338 shares of common
                      stock. Dr. Caruso disclaims beneficial ownership of shares
                      held by Tru St and Provco Leasing except to the extent of
                      his pecuniary interest therein.


                                                              Page 6 of 10 Pages

                  (b) Percent of Class: Based on 28,265,615 shares of the
                      Issuer's common stock outstanding as of January 27, 2006
                      as reported in Schedule 13D (Amendment No. 2) of Stuart M.
                      Essig dated January 31, 2006: Dr. Caruso may be deemed the
                      beneficial owner of 25.47% of the Issuer's common stock;
                      Tru St, may be deemed the beneficial owner of 25.09% of
                      the Issuer's common stock; and Provco Leasing may be
                      deemed the beneficial owner of 25.17% of the Issuer's
                      common stock.

                  (c) The Reporting Persons have the power to vote or dispose of
                      the number of shares as follows:

                           (i)      Sole power to vote or direct the vote. Dr.
                                    Caruso may be deemed to have sole power to
                                    vote or direct the vote of 85,624 shares of
                                    common stock based on his ownership of 624
                                    shares and options to purchase 85,000 shares
                                    of common stock that are exercisable within
                                    60 days of February 1, 2006.

                           (ii)     Shared power to vote or direct the vote. Dr.
                                    Caruso, Tru St and Provco Leasing may be
                                    deemed to share the power to vote or direct
                                    the vote with respect to 7,091,205 shares of
                                    common stock. Dr. Caruso and Provco Leasing
                                    may be deemed to share the power to vote or
                                    direct the vote with respect to 23,338
                                    shares of common stock.

                           (iii)    Sole power to dispose or direct the
                                    disposition. Dr. Caruso has sole power to
                                    dispose or control the disposition of 85,624
                                    shares of common stock based on his
                                    ownership of 624 shares and options to
                                    purchase 85,000 shares of common stock that
                                    are exercisable within 60 days of February
                                    1, 2006.

                            (iv)    Shared power to dispose or direct the
                                    disposition. Dr. Caruso, Tru St and Provco
                                    Leasing may be deemed to have shared power
                                    to dispose of or shared power to direct the
                                    disposition of 7,091,205 shares of common
                                    stock. Dr. Caruso and Provco Leasing may be
                                    deemed to have shared power to dispose of or
                                    shared power to direct the disposition of
                                    23,338 shares of common stock.

Item 5.           Ownership of Five Percent or less of a Class:

                  Not applicable.

Item 6.           Ownership of More Than Five Percent on Behalf of Another
                  Person:

                  Not applicable

Item 7.           Identification and Classification of the Subsidiary which
                  Acquired the Security Reported on by the Parent Holding
                  Company:

                  Not applicable

Item 8.           Identification and Classification of Members of the Group:

                  Exhibit A attached hereto identifies each member of the group
                  filing this Schedule 13G/A pursuant to Rule 13d-1(d).


                                                              Page 7 of 10 Pages

Item 9.           Notice of Dissolution of Group:
                  Not applicable

Item 10.          Certification:  Not applicable.


                                    Signature

         After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.


Date:    February 9, 2006
                                            /s/ Richard E. Caruso, Ph.D.
                                            ----------------------------


TRU ST PARTNERSHIP LP

Provco Leasing Corporation, GP



By: /s/ Richard E. Caruso, Ph.D.
    ----------------------------
Its:    President


PROVCO LEASING CORPORATION



By: /s/ Richard E. Caruso, Ph.D.
    ----------------------------
Its:    President




                                                              Page 8 of 10 Pages


                                  Exhibit Index

Exhibit                           Title                              Page No.

Exhibit A                         Group Members                          9

Exhibit B                         Joint Filing Agreement                10



                                                              Page 9 of 10 Pages


                                    EXHIBIT A


                                  Group Members


                            Richard E. Caruso, Ph.D.
                              Tru St Partnership LP
                           Provco Leasing Corporation



                                                             Page 10 of 10 Pages


                                    EXHIBIT B

                             Joint Filing Agreement

         In accordance with Rule 13d-1(k) under the Securities Exchange Act of
1934, as amended, the persons named below agree to the joint filing on behalf of
each of them of a Statement on Schedule 13G/A (including amendments thereto)
with respect to the common stock, par value $.01 per share of Integra
LifeSciences Holdings Corporation, and further agree that this Joint Filing
Agreement be included as Exhibit to such joint filings. In evidence thereof, the
undersigned, being duly authorized, have executed this Joint Filing Agreement
this 9th day of February 2006.


TRU ST PARTNERSHIP LP

Provco Leasing Corporation, GP


By: /s/ Richard E. Caruso, Ph.D.         By: /s/ Richard E. Caruso, Ph.D.
    ---------------------------              ----------------------------
Its:    President


PROVCO LEASING CORPORATION


By: /s/ Richard E. Caruso, Ph.D.
    ---------------------------
Its:    President