SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC  20549

SCHEDULE 13D
(Rule 13d-101)

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 8)*

Regeneron Pharmaceuticals, Inc.
(Name of Issuer)

Common Stock, $0.001 par value
(Title of Class of Securities)

75886F 10 7
(CUSIP Number)

Karen Linehan
Executive Vice President, Legal Affairs and General Counsel
Sanofi
54, rue La Boétie, 75008
Paris, France
Telephone: +33 1 53 77 40 00

Copy to:

Michael J. Aiello, Esq.
Weil, Gotshal & Manges LLP
767 Fifth Avenue
New York, New York 10153
(212) 310-8000
(Name, Address and Telephone Number of Person
Authorized to Receive Notices and Communications)
 
July 7, 2014
(Date of Event Which Requires Filing of This Statement)

If the filing person has previously filed a statement on Schedule 13G to report the acquisition which is the subject of this Schedule 13D, and is filing this schedule because of Rule 13d-1(e), 13d-1(f) or 13d-1(g), check the following box.  x 

Note.  Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits.  See Rule 13d-7 for other parties to whom copies are to be sent.

*The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).
 
13D
 
1.
NAME OF REPORTING PERSONS
Sanofi
 
  
 
   
2.
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(a) o
(b) o
  
 
   
3.
SEC USE ONLY
 
  
 
     
4.
SOURCE OF FUNDS         WC
 
  
 
     
5.
CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e)           ¨
 
  
 
    
6.
CITIZENSHIP OR PLACE OF ORGANIZATION
The Republic of France
   
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY EACH
REPORTING PERSON
WITH
 
7.
 
SOLE VOTING POWER         -0-
 
8.
 
SHARED VOTING POWER  21,405,741 (1)
 
9.
 
SOLE DISPOSITIVE POWER         -0-
 
10.
 
SHARED DISPOSITIVE POWER  21,405,741 (1)
11.
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON  21,405,741 (1)
  
 
12.
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES            ¨
 
 
13.
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)       21.6% (2)
 
 
14.
TYPE OF REPORTING PERSON                            CO
 
(1)            18,606,189 shares of Common Stock are held directly by sanofi-aventis Amérique du Nord (“SAAN”) and 2,799,552 of the shares of Common Stock are held directly by Aventis Pharmaceuticals Inc. (“Aventis”).   SAAN is a direct, wholly-owned subsidiary of Sanofi.  Aventis is an indirect, wholly-owned subsidiary of SAAN.  See Item 5 of the Schedule 13D.  Pursuant to the Amended and Restated Investor Agreement, dated as of January 11, 2014, by and among Sanofi, SAAN, sanofi-aventis US LLC, Aventis (collectively, the “Sanofi Parties”) and Regeneron Pharmaceuticals, Inc. (the “Company”), the Sanofi Parties have agreed to vote their respective shares of the Company, subject to specified exceptions, in accordance with the recommendation of the Company’s Board of Directors.

(2)            Calculation based on 98,879,794 shares of Common Stock outstanding as of April 17, 2014, as reported in the Company’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on May 8, 2014.

2
This Amendment No. 8 (this “Amendment No. 8”) amends the Statement on Schedule 13D first filed with the Securities and Exchange Commission on January 14, 2014, as amended (the “Schedule 13D”), and is filed by Sanofi (“Sanofi” or the “Reporting Person”) with respect to the common stock, $0.001 par value per share (the “Common Stock”), of Regeneron Pharmaceuticals, Inc. (the “Issuer” or the “Company”).  Capitalized terms used herein but not otherwise defined herein have the meanings given to them in the Schedule 13D.
 
Item 3.
Source and Amount of Funds or Other Consideration.

Item 3 of the Schedule 13D is supplemented as follows:

 For the purchases it made as disclosed in Item 5(c) of this Amendment No. 8, SAAN paid an aggregate of $348,139,911.15, excluding brokerage commission and fees.  The source of such funds was working capital.

Item 4.
Purpose of Transaction.

Item 4 of the Schedule 13D is supplemented as follows:
 
The Reporting Person purchased, through its subsidiary SAAN, an aggregate of 1,146,900 shares of Common Stock in market transactions, as disclosed in Item 5(c) of this Amendment No. 8.

Item 5.
Interests in the Securities of the Issuer.

Item 5 of the Schedule 13D is supplemented as follows:
 
(a) and (b)  The responses of the Reporting Person to Rows (7) through (13) of the cover page of this Amendment No. 8 as of the close of business on July 8, 2014, are incorporated herein by reference.  As of the close of business on July 8, 2014, the Reporting Person beneficially owned 21,405,741 shares of Common Stock, representing approximately 21.6% of the shares of Common Stock outstanding (based on 98,879,794 shares of Common Stock outstanding as of April 17, 2014, as reported in the Company’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on May 8, 2014).  The Reporting Person may be deemed to have shared voting and dispositive power with respect to the shares of Common Stock directly owned by SAAN and Aventis, its subsidiaries.
 
To the Reporting Person’s knowledge, none of the directors or executive officers of the Reporting Persons listed on Schedule I to the Schedule 13D beneficially owns any shares of Common Stock as of July 8, 2014.
 
(c)  Since the most recent filing of Schedule 13D and through and including July 8, 2014, market transactions were effected in the Common Stock as disclosed in Schedule A to this Amendment No. 8.
 
To the Reporting Person’s knowledge, none of the directors or executive officers of the Reporting Person listed on Schedule I to the Schedule 13D effected transactions in the Common Stock during the period described above.
 
(d)  Not applicable.
 
(e)  Not applicable.
3
SIGNATURE

After reasonable inquiry and to the best of its knowledge and belief, the undersigned certifies that the information set forth in this statement is true, complete and correct.

Dated:  July 9, 2014
 
 
SANOFI
 
 
By:
/s/ John Felitti
 
 
Name:
John Felitti
 
 
Title:
Associate Vice President, Corporate Law,
 
 
 
Financial & Securities Law
4
Schedule A

Entity
Trade Date
  (M/D/Y)†
Transaction
  
Number of Shares of Common Stock*
    
Price per
 Share*
    
Price Range*
  
 
SAAN
6/30/2014
Purchase
    
524
    
$
275.6790
    
$
275.05
    
$
276.00
  
SAAN
6/30/2014
Purchase
    
4,725
    
$
276.3318
    
$
276.06
    
$
277.00
  
SAAN
6/30/2014
Purchase
    
1,600
    
$
277.2944
    
$
277.10
    
$
278.09
  
SAAN
6/30/2014
Purchase
    
3,160
    
$
278.3020
    
$
278.10
    
$
278.98
  
SAAN
6/30/2014
Purchase
    
6,844
    
$
280.0328
    
$
279.29
    
$
280.28
  
SAAN
6/30/2014
Purchase
    
20,665
    
$
280.7446
    
$
280.30
    
$
281.29
  
SAAN
6/30/2014
Purchase
    
25,643
    
$
281.8940
    
$
281.32
    
$
282.31
  
SAAN
6/30/2014
Purchase
    
79,511
    
$
282.9111
    
$
282.32
    
$
283.31
  
SAAN
6/30/2014
Purchase
    
62,704
    
$
283.8328
    
$
283.32
    
$
284.31
  
SAAN
6/30/2014
Purchase
    
7,024
    
$
284.5270
    
$
284.33
    
$
284.92
  
SAAN
7/1/2014
Purchase
    
600
    
$
285.8900
    
$
285.55
    
$
286.25
  
SAAN
7/1/2014
Purchase
    
930
    
$
287.0772
    
$
286.69
    
$
287.50
  
SAAN
7/1/2014
Purchase
    
543
    
$
288.2412
    
$
287.74
    
$
288.72
  
SAAN
7/1/2014
Purchase
    
689
    
$
289.3166
    
$
289.00
    
$
289.53
  
SAAN
7/1/2014
Purchase
    
3,513
    
$
292.9795
    
$
292.50
    
$
293.38
  
SAAN
7/1/2014
Purchase
    
5,001
    
$
294.2568
    
$
293.67
    
$
294.64
  
SAAN
7/1/2014
Purchase
    
11,155
    
$
295.0946
    
$
294.68
    
$
295.53
  
SAAN
7/1/2014
Purchase
    
10,463
    
$
296.3817
    
$
295.70
    
$
296.67
  
SAAN
7/1/2014
Purchase
    
20,472
    
$
297.2576
    
$
296.72
    
$
297.69
  
SAAN
7/1/2014
Purchase
    
8,238
    
$
298.1332
    
$
297.72
    
$
298.68
  
SAAN
7/1/2014
Purchase
    
16,683
    
$
299.1603
    
$
298.73
    
$
299.72
  
SAAN
7/1/2014
Purchase
    
18,074
    
$
300.2167
    
$
299.73
    
$
300.72
  
SAAN
7/1/2014
Purchase
    
39,530
    
$
301.2295
    
$
300.73
    
$
301.70
  
SAAN
7/1/2014
Purchase
    
11,932
    
$
302.3760
    
$
301.79
    
$
302.76
  
SAAN
7/1/2014
Purchase
    
42,419
    
$
303.2385
    
$
302.80
    
$
303.79
  
SAAN
7/1/2014
Purchase
    
22,158
    
$
304.0121
    
$
303.80
    
$
304.41
  
SAAN
7/2/2014
Purchase
    
6,151
    
$
298.9059
    
$
298.29
    
$
299.28
  
SAAN
7/2/2014
Purchase
    
18,945
    
$
299.8729
    
$
299.29
    
$
300.28
  
SAAN
7/2/2014
Purchase
    
10,900
    
$
300.5558
    
$
300.32
    
$
301.19
  
SAAN
7/2/2014
Purchase
    
6,673
    
$
301.6310
    
$
301.36
    
$
302.00
  
SAAN
7/2/2014
Purchase
    
1,700
    
$
303.0229
    
$
302.59
    
$
303.54
  
SAAN
7/2/2014
Purchase
    
2,425
    
$
304.1930
    
$
303.73
    
$
304.68
  
SAAN
7/2/2014
Purchase
    
8,741
    
$
305.2062
    
$
304.75
    
$
305.60
  
SAAN
7/2/2014
Purchase
    
7,138
    
$
306.3395
    
$
305.77
    
$
306.76
  
SAAN
7/2/2014
Purchase
    
18,997
    
$
307.2525
    
$
306.77
    
$
307.76
  
SAAN
7/2/2014
Purchase
    
35,400
    
$
308.4334
    
$
307.81
    
$
308.80
  
SAAN
7/2/2014
Purchase
    
30,530
    
$
309.3588
    
$
308.81
    
$
309.80
  
5
Entity
Trade Date
  (M/D/Y)†
Transaction
Number of Shares of Common Stock*
Price per
 Share*
Price Range*
 
SAAN
7/2/2014
Purchase
    
28,290
    
$
310.1358
    
$
309.81
    
$
310.80
  
SAAN
7/2/2014
Purchase
    
30,510
    
$
311.3193
    
$
310.81
    
$
311.80
  
SAAN
7/2/2014
Purchase
    
6,000
    
$
311.9243
    
$
311.81
    
$
312.11
  
SAAN
7/3/2014
Purchase
    
15,953
    
$
309.4638
    
$
308.73
    
$
309.72
  
SAAN
7/3/2014
Purchase
    
24,877
    
$
310.2112
    
$
309.73
    
$
310.71
  
SAAN
7/3/2014
Purchase
    
31,358
    
$
311.1989
    
$
310.73
    
$
311.72
  
SAAN
7/3/2014
Purchase
    
20,376
    
$
312.2828
    
$
311.73
    
$
312.71
  
SAAN
7/3/2014
Purchase
    
7,436
    
$
312.8424
    
$
312.73
    
$
312.97
  
SAAN
7/7/2014
Purchase
    
14,852
    
$
311.1676
    
$
310.48
    
$
311.47
  
SAAN
7/7/2014
Purchase
    
102,911
    
$
312.0998
    
$
311.48
    
$
312.47
  
SAAN
7/7/2014
Purchase
    
72,706
    
$
312.8645
    
$
312.48
    
$
313.44
  
SAAN
7/7/2014
Purchase
    
30,731
    
$
314.0601
    
$
313.50
    
$
314.43
  
SAAN
7/7/2014
Purchase
    
33,408
    
$
314.9575
    
$
314.50
    
$
315.49
  
SAAN
7/7/2014
Purchase
    
2,092
    
$
315.5946
    
$
315.50
    
$
315.65
  
SAAN
7/8/2014
Purchase
    
9,985
    
$
309.3301
    
$
308.76
    
$
309.74
  
SAAN
7/8/2014
Purchase
    
37,790
    
$
310.3359
    
$
309.75
    
$
310.73
  
SAAN
7/8/2014
Purchase
    
42,745
    
$
311.2548
    
$
310.75
    
$
311.74
  
SAAN
7/8/2014
Purchase
    
17,014
    
$
312.1152
    
$
311.75
    
$
312.68
  
SAAN
7/8/2014
Purchase
    
32,331
    
$
313.0924
    
$
312.74
    
$
313.68
  
SAAN
7/8/2014
Purchase
    
8,229
    
$
314.4147
    
$
313.77
    
$
314.69
  
SAAN
7/8/2014
Purchase
    
4,906
    
$
314.8523
    
$
314.79
    
$
315.00
  
 
*The number of securities reported represents an aggregate number of shares executed by a broker-dealer in multiple market transactions over a range of prices.  The price per share reported represents the weighted average price (without regard to brokerage commissions and fees).  The Reporting Person undertakes to provide the staff of the SEC upon request, the number of shares executed by such Reporting Person at each separate price within the range.
 
†SAAN purchased the shares of Common Stock pursuant to a plan intended to comply with Rule 10b5-1(c)(1)(i) under the Exchange Act, entered into with a broker on June 27, 2014.
 
 
6