13G HTML File DOCUMENT TYPE SC 13G
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SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
Under the Securities Exchange Act of 1934


Name of Issuer: Kayne Anderson MLP/Midstream Investment Co
_____________________________________________________
Title of Class
of Securities: Preferred Stock

CUSIP Number: 4866068#6

1) NAME AND I.R.S. IDENTIFICATION NO. OF REPORTING PERSON

Prudential Financial, Inc. 22-3703799

2.) MEMBER OF A GROUP: (a) N/A
(b) N/A

3) SEC USE ONLY:



4) PLACE OF ORGANIZATION: New Jersey

NUMBER OF SHARES BENEFICIALLY OWNED BY REPORTING PERSON WITH:

5) Sole Voting Power: 1,000,000 See Exhibit A
6) Shared Voting Power: 0 See Exhibit A
7) Sole Dispositive Power: 1,000,000 See Exhibit A
8) Shared Dispositive Power: 0 See Exhibit A

9) AGGREGATE AMOUNT BENEFICIALLY OWNED: 1,000,000 See Exhibit A

10) AGGREGATE AMOUNT IN ROW (9) EXCLUDES SHARES: Not Applicable

11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9): 7.9 See Exhibit A

12) TYPE OF REPORTING PERSON: HC

ITEM 1(a). NAME OF ISSUER:

Kayne Anderson MLP/Midstream Investment Co

ITEM 1(b). ADDRESS OF ISSUER'S EXECUTIVE OFFICES:

717 TEXAS AVENUE
SUITE 3100
HOUSTON, TX 77002


ITEM 2(a). NAME OF PERSON FILING:

Prudential Financial, Inc.

ITEM 2(b). ADDRESS OF PRINCIPAL BUSINESS OFFICE:

751 Broad Street
Newark, New Jersey 07102-3777

ITEM 2(c). CITIZENSHIP:

New Jersey

ITEM 2(d). TITLE OF CLASS OF SECURITIES:

Preferred Stock

ITEM 2(e). CUSIP NUMBER:

4866068#6

ITEM 3. The Person filing this statement is a Parent Holding Company as
defined in Section 240.13d-1(b)(1)(ii)(G) of the Securities Exchange
Act of 1934.

ITEM 4. OWNERSHIP:

(a) Number of Shares
Beneficially Owned: 1,000,000
See Exhibit A

(b) Percent of Class: 7.9


(c) Powers                No. Of Shares
----------- --------------------
Sole power to vote or 1,000,000 See Exhibit A to direct the vote
Shared power to vote or 0 See Exhibit A to direct the vote
Sole power to dispose or 1,000,000 See Exhibit A to direct disposition
Shared power to dispose 0 See Exhibit A or to direct disposition

ITEM 5. OWNERSHIP OF 5% OR LESS OF A CLASS:

Not Applicable

ITEM 6. OWNERSHIP OF MORE THAN 5% ON BEHALF OF
ANOTHER PERSON:
Prudential Retirement Insurance and Annuity Company, an indirect wholly-owned
subsidiary of the Reporting Person, may have the right to receive or the power
to direct the receipt of dividends from, or the proceeds from the sale of, such
securities which are the subject of this filing.

ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE
SUBSIDIARY WHICH ACQUIRED THE SECURITY BEING
REPORTED ON BY THE ULTIMATE PARENT COMPANY:

See Exhibit A

ITEM 8. IDENTIFICATION AND CLASSIFICATION OF
MEMBERS OF THE GROUP:

Not Applicable

ITEM 9. NOTICE OF DISSOLUTION OF GROUP:

Not Applicable

ITEM 10. CERTIFICATION:

By signing below, Prudential Financial, Inc. certifies that, to the best of its
knowledge and belief, the securities referred to above were acquired
and are held in the ordinary course of business and were not acquired
and are not held for the purpose of or with the effect of changing or
influencing the control of the issuer of the securities and were not acquired
and are not held in connection with or as a participant in any transaction
having that purpose or effect.


The filing of this statement should not be construed as an admission that
Prudential Financial, Inc. is, for purposes of Sections 13 or 16 of the Securities
Exchange Act of 1934, the beneficial owner of such shares.


SIGNATURE

After reasonable inquiry and to the best of its knowledge and belief,
Prudential Financial, Inc. certifies that the information set forth in this
statement is true, complete and correct.

PRUDENTIAL FINANCIAL, INC.

By: Hillary Lorenzo
Vice President

Date: 02/04/2019
As of: 12/31/2018

Exhibit A
--------------

ITEM 4. OWNERSHIP:

All outstanding Preferred Share Securities of Kayne Anderson Energy Development
Company (ticker: KED) were replaced by Preferred Share Securities of Kayne
Anderson MLP/Midstream Investment Company (ticker: KYN; cusip: 4866068#6) in
connection with the merger of KED into KYN, effective 8/6/2018.  Through its
parent/subsidiary relationship, Prudential Financial, Inc. may be deemed the
beneficial owner of the same securities as the Item 7 listed subsidiaries and
may have direct or indirect voting and/or investment discretion over 1,000,000
shares.

These shares were acquired in the ordinary course of business, and not with the
purpose or effect of changing or influencing control of the Issuer.  The filing
of this statement should not be construed as an admission that Prudential
Financial, Inc. is, for the purposes of Sections 13 or 16 of the Securities
Exchange Act of 1934, the beneficial owner of these shares.
Rule 13d-1(k)(1) JOINT FILING AGREEMENT Each of the undersigned hereby agrees and consents to the execution and joint filing on its behalf of this Schedule 13G in connection with the beneficial ownership of the securities which are the subject of this schedule. Dated this 4th day of February, 2019 Prudential Financial, Inc. By: /s/ Hillary Lorenzo Vice President Prudential Retirement Insurance and Annuity Company By: /s/ Christopher L. Halloran Vice President PGIM, Inc., as Investment Manager By: /s/ Christopher L. Halloran Vice President

ITEM 7. IDENTIFICATION/CLASSIFICATION:

Prudential Financial, Inc. is a Parent Holding Company and the indirect parent
of the following subsidiaries, who are the beneficial owners of the number and
percentage of securities which are the subject of this filing as set forth next
to their names:



Subsidiaries Number of Shares Percentage
The Prudential Insurance Company of America IC 0 0
Prudential Retirement Insurance and Annuity Company IC 1,000,000 7.9
Jennison Associates LLC IA 0 0
PGIM, Inc. IA 1,000,000 7.9
Quantitative Management Associates LLC IA 0 0